WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555902

CAS#: 2314467-60-0 (HCl)

Description: OUN67600, is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation. OUN67600 was first reported by Atobe et al (compound 36 in J Med Chem. 2019 Feb 14;62(3):1468-1483). OUN67600 has CAS#2314467-60-0, no formal name. For the convenience of scientific communication, we named it as OUN67600 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).

Chemical Structure

CAS# 2314467-60-0 (HCl)

Theoretical Analysis

MedKoo Cat#: 555902
Name: OUN67600
CAS#: 2314467-60-0 (HCl)
Chemical Formula: C25H23ClF2N4O2
Exact Mass:
Molecular Weight: 484.9318
Elemental Analysis: C, 61.92; H, 4.78; Cl, 7.31; F, 7.84; N, 11.55; O, 6.60

Size Price Shipping out time Quantity
100mg USD 1650 2 Weeks
200mg USD 2650 2 Weeks
500mg USD 2650 2 Weeks
1g USD 4650 2 Weeks
2g USD 7450 2 Weeks
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Pricing updated 2021-02-28. Prices are subject to change without notice.

OUN67600 is in stock.

Related CAS #: 2314467-60-0 (HCl)   2314467-59-7 (free base)    

Synonym: OUN67600; OUN-67600; ; OUN 67600; TRPV4 Agonist;

IUPAC/Chemical Name: 4(3H)-Quinazolinone, 8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methyl-1-piperazinyl)-, hydrochloride (1:1)


InChi Code: InChI=1S/C25H22F2N4O2.ClH/c1-29-13-15-30(16-14-29)25-28-23-21(3-2-4-22(23)27)24(32)31(25)18-7-11-20(12-8-18)33-19-9-5-17(26)6-10-19;/h2-12H,13-16H2,1H3;1H


Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 484.9318 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Atobe M, Nagami T, Muramatsu S, Ohno T, Kitagawa M, Suzuki H, Ishiguro M, Watanabe A, Kawanishi M. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483. doi: 10.1021/acs.jmedchem.8b01615. Epub 2019 Jan 28. PMID: 30629441.