Motuporamine A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463702

CAS#: unknown

Description: Motuporamine A is a natural product isolated from the tropical sponge Xestospongia exigua.


Chemical Structure

img
Motuporamine A
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463702
Name: Motuporamine A
CAS#: unknown
Chemical Formula: C18H39N3
Exact Mass: 297.31
Molecular Weight: 297.531
Elemental Analysis: C, 72.66; H, 13.21; N, 14.12

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Motuporamine A; Motuporamine-A;

IUPAC/Chemical Name: N1-(3-(azacyclotridecan-1-yl)propyl)propane-1,3-diamine

InChi Key: AXRQFIIUYLOARV-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H39N3/c19-13-11-14-20-15-12-18-21-16-9-7-5-3-1-2-4-6-8-10-17-21/h20H,1-19H2

SMILES Code: NCCCNCCCN1CCCCCCCCCCCC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 297.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Borselli D, Blanchet M, Bolla JM, Muth A, Skruber K, Phanstiel O 4th, Brunel JM. Motuporamine Derivatives as Antimicrobial Agents and Antibiotic Enhancers against Resistant Gram-Negative Bacteria. Chembiochem. 2017 Feb 1;18(3):276-283. doi: 10.1002/cbic.201600532. Epub 2017 Jan 18. PMID: 28098416; PMCID: PMC5299527.

2: Weston MH, Nakajima K, Back TG. Tandem conjugate additions and 3-aza-Cope rearrangements of tertiary allyl amines and cyclic alpha-vinylamines with acetylenic sulfones. Applications to simple and iterative ring expansions leading to medium and large-ring nitrogen heterocycles. J Org Chem. 2008 Jun 20;73(12):4630-7. doi: 10.1021/jo800600a. Epub 2008 May 23. PMID: 18498198.

3: Williams DE, Craig KS, Patrick B, McHardy LM, van Soest R, Roberge M, Andersen RJ. Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. J Org Chem. 2002 Jan 11;67(1):245-58. doi: 10.1021/jo016101c. PMID: 11777468.

4: Goldring WP, Weiler L. Cytotoxic alkaloids motuporamines A-C: synthesis and structural verification. Org Lett. 1999 Nov 4;1(9):1471-3. doi: 10.1021/ol991029e. Erratum in: Org Lett 1999 Dec 2;1(11):1874. PMID: 10825995.