VU0415248

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463701

CAS#: unknown

Description: VU0415248 is a M1R-selective antagonist.


Chemical Structure

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VU0415248
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463701
Name: VU0415248
CAS#: unknown
Chemical Formula: C21H23N5O3S
Exact Mass: 425.1522
Molecular Weight: 425.507
Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.53

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: VU0415248; VU 0415248; VU-0415248;

IUPAC/Chemical Name: N-(3-oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)quinoline-5-sulfonamide

InChi Key: KZEVRYRKBGRMEZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H23N5O3S/c27-21(26-15-13-25(14-16-26)17-6-10-22-11-7-17)8-12-24-30(28,29)20-5-1-4-19-18(20)3-2-9-23-19/h1-7,9-11,24H,8,12-16H2

SMILES Code: O=S(C1=C(C=CC=N2)C2=CC=C1)(NCCC(N3CCN(C4=CC=NC=C4)CC3)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 425.507 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Melancon BJ, Lamers AP, Bridges TM, Sulikowski GA, Utley TJ, Sheffler DJ, Noetzel MJ, Morrison RD, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Wood MR. Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1044-8. doi: 10.1016/j.bmcl.2011.11.110. Epub 2011 Dec 6. PMID: 22197142; PMCID: PMC3434972.