WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463701
Description: VU0415248 is a M1R-selective antagonist.
MedKoo Cat#: 463701
Chemical Formula: C21H23N5O3S
Exact Mass: 425.1522
Molecular Weight: 425.507
Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.53
This product is not in stock, which may be available by custom synthesis.
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Synonym: VU0415248; VU 0415248; VU-0415248;
IUPAC/Chemical Name: N-(3-oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)quinoline-5-sulfonamide
InChi Key: KZEVRYRKBGRMEZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H23N5O3S/c27-21(26-15-13-25(14-16-26)17-6-10-22-11-7-17)8-12-24-30(28,29)20-5-1-4-19-18(20)3-2-9-23-19/h1-7,9-11,24H,8,12-16H2
SMILES Code: O=S(C1=C(C=CC=N2)C2=CC=C1)(NCCC(N3CCN(C4=CC=NC=C4)CC3)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 425.507 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Melancon BJ, Lamers AP, Bridges TM, Sulikowski GA, Utley TJ, Sheffler DJ, Noetzel MJ, Morrison RD, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Wood MR. Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1044-8. doi: 10.1016/j.bmcl.2011.11.110. Epub 2011 Dec 6. PMID: 22197142; PMCID: PMC3434972.