WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463691
Description: YB-9 is a novel Aβ-disaggregator, disaggregating Aβ plaques and oligomers in the brain of 5XFAD Alzheimer transgenic mouse.
MedKoo Cat#: 463691
Chemical Formula: C18H16O6
Exact Mass: 328.0947
Molecular Weight: 328.32
Elemental Analysis: C, 65.85; H, 4.91; O, 29.24
This product is not in stock, which may be available by custom synthesis.
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Synonym: YB-9; YB9; YB 9;
IUPAC/Chemical Name: 2-((5-methoxy-3-(4-methoxyphenyl)benzofuran-6-yl)oxy)acetic acid
InChi Key: XBKOMNZVOFQSSG-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H16O6/c1-21-12-5-3-11(4-6-12)14-9-23-15-8-17(24-10-18(19)20)16(22-2)7-13(14)15/h3-9H,10H2,1-2H3,(H,19,20)
SMILES Code: O=C(O)COC1=C(OC)C=C2C(C3=CC=C(OC)C=C3)=COC2=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 328.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kim D, Bae GH, Kim HY, Jeon H, Kim K, Shin J, Lee S, Hong S, Kim I, Kim Y. Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse. ACS Chem Neurosci. 2020 Dec 17. doi: 10.1021/acschemneuro.0c00606. Epub ahead of print. PMID: 33332107.