WAY-100135 hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463676

CAS#: 149007-54-5 (hydrochloride)

Description: WAY-100135 hydrochloride is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1A. It is selective for 5-HT1A over 5-HT1B, 5-HT1C, and 5-HT2 receptors, as well as dopamine D1 and D2, and α1-, α2-, and β-adrenergic receptors. WAY-100135 hydrochloride increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.

Chemical Structure

WAY-100135 hydrochloride
CAS# 149007-54-5 (hydrochloride)

Theoretical Analysis

MedKoo Cat#: 463676
Name: WAY-100135 hydrochloride
CAS#: 149007-54-5 (hydrochloride)
Chemical Formula: C24H35Cl2N3O2
Exact Mass: 467.2106
Molecular Weight: 468.463
Elemental Analysis: C, 61.53; H, 7.53; Cl, 15.13; N, 8.97; O, 6.83

Price and Availability

Size Price Availability Quantity
5.0mg USD 240.0 2 Weeks
10.0mg USD 390.0 2 Weeks
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Related CAS #: 149007-54-5 (hydrochloride)   133025-23-7 (free)  

Synonym: WAY-100135 hydrochloride; WAY 100135 hydrochloride; WAY100135 hydrochloride; (S)-WAY-100135 hydrochloride; (S)-WAY100135 hydrochloride; (S)-WAY 100135 hydrochloride;

IUPAC/Chemical Name: (S)-N-(tert-butyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)-2-phenylpropanamide dihydrochloride


InChi Code: InChI=1S/C24H33N3O2.2ClH/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4;;/h5-13,20H,14-18H2,1-4H3,(H,25,28);2*1H/t20-;;/m1../s1

SMILES Code: COC1=C(C=CC=C1)N2CCN(C[C@@H](C(NC(C)(C)C)=O)C3=CC=CC=C3)CC2.Cl.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 468.463 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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