Zamifenacin fumarate
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MedKoo CAT#: 463667

CAS#: 127308-98-9 (fumarate)

Description: Zamifenacin fumarate is an antagonist of M3 muscarinic acetylcholine receptors. It is selective for M3 over M1, M2, M4, and M5 receptors in radioligand binding assays using cells expressing recombinant human receptors. Zamifenacin fumarate inhibits cholecystokinin-induced small bowel motility but does not increase heart rate in dogs.


Chemical Structure

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Zamifenacin fumarate
CAS# 127308-98-9 (fumarate)

Theoretical Analysis

MedKoo Cat#: 463667
Name: Zamifenacin fumarate
CAS#: 127308-98-9 (fumarate)
Chemical Formula: C31H33NO7
Exact Mass: 531.2257
Molecular Weight: 531.605
Elemental Analysis: C, 70.04; H, 6.26; N, 2.63; O, 21.07

Price and Availability

Size Price Availability Quantity
1.0mg USD 210.0 2 Weeks
5.0mg USD 380.0 2 Weeks
10.0mg USD 590.0 2 Weeks
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Related CAS #: 127308-98-9 (fumarate)   127308-82-1 (free)  

Synonym: Zamifenacin fumarate; UK 76654; UK76654; UK-76654;

IUPAC/Chemical Name: (R)-3-(benzhydryloxy)-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)piperidine fumarate

InChi Key: PMHKTAIGYOVZEZ-ZHWJIHCSSA-N

InChi Code: InChI=1S/C27H29NO3.C4H4O4/c1-3-8-22(9-4-1)27(23-10-5-2-6-11-23)31-24-12-7-16-28(19-24)17-15-21-13-14-25-26(18-21)30-20-29-25;5-3(6)1-2-4(7)8/h1-6,8-11,13-14,18,24,27H,7,12,15-17,19-20H2;1-2H,(H,5,6)(H,7,8)/b;2-1+/t24-;/m1./s1

SMILES Code: OC(/C=C/C(O)=O)=O.C(C1=CC=CC=C1)(O[C@H]2CN(CCC3=CC=C4OCOC4=C3)CCC2)C5=CC=CC=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 531.605 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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