VU0155056
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412718

CAS#: 1130067-18-3

Description: VU0155056 is a cell-permeable phospholipase D1 and D2 inhibitor.


Chemical Structure

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VU0155056
CAS# 1130067-18-3

Theoretical Analysis

MedKoo Cat#: 412718
Name: VU0155056
CAS#: 1130067-18-3
Chemical Formula: C25H26N4O2
Exact Mass: 414.2056
Molecular Weight: 414.51
Elemental Analysis: C, 72.44; H, 6.32; N, 13.52; O, 7.72

Price and Availability

Size Price Availability Quantity
1.0mg USD 328.0 2 Weeks
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Synonym: VU0155056; N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide

IUPAC/Chemical Name: N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide

InChi Key: IXLLRNNFUYEADZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)

SMILES Code: O=C1N(C2CCN(CCNC(C3=CC(C=CC=C4)=C4C=C3)=O)CC2)C5=CC=CC=C5N1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 414.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Kumar M, Ojha S1, Rai P, Joshi A, Kamat SS, Mallik R. Insulin activates intracellular transport of lipid droplets to release triglycerides from the liver. J Cell Biol. 2019 Nov 4;218(11):3697-3713. doi: 10.1083/jcb.201903102. Epub 2019 Oct 11.

PubMed ID: 31604801

2. Scott SA, Selvy PE, Buck JR, Cho HP, Criswell TL, Thomas AL, Armstrong MD, Arteaga CL, Lindsley CW, Brown HA. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17. doi: 10.1038/nchembio.140. Epub 2009 Jan 11.

PubMed ID: 19136975