WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 575297
Description: Fagaramide is a biochemical that is cytotoxic against species against multidrug resistant leukemia cells.
MedKoo Cat#: 575297
Chemical Formula: C14H17NO3
Exact Mass: 247.1208
Molecular Weight: 247.29
Elemental Analysis: C, 68.00; H, 6.93; N, 5.66; O, 19.41
This product is not in stock, which may be available by custom synthesis.
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IUPAC/Chemical Name: 2-Propenamide, 3-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-, (E)- (9CI)
InChi Key: WKWYNAMJWDRHBP-XQRVVYSFSA-N
InChi Code: InChI=1S/C14H17NO3/c1-10(2)8-15-14(16)6-4-11-3-5-12-13(7-11)18-9-17-12/h3-7,10H,8-9H2,1-2H3,(H,15,16)/b6-4-
SMILES Code: CC(C)CNC(=O)\C=C/c1ccc2OCOc2c1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 247.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Omosa LK, Mbogo GM, Korir E, Omole R, Seo EJ, Yenesew A, Heydenreich M, Midiwo JO, Efferth T. Cytotoxicity of fagaramide derivative and canthin-6-one from Zanthoxylum (Rutaceae) species against multidrug resistant leukemia cells. Nat Prod Res. 2019 Mar 21:1-8. doi: 10.1080/14786419.2019.1587424. Epub ahead of print. PMID: 30896260.