DB04763

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463521

CAS#: unknown

Description: DB04763 is a native allosteric modulator of α7 nAChR.

Chemical Structure

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DB04763
CAS# unknown
Instruction

Theoretical Analysis

MedKoo Cat#: 463521
Name: DB04763
CAS#: unknown
Chemical Formula: C16H21BF4N2O2S
Exact Mass: 392.14
Molecular Weight: 392.220
Elemental Analysis: C, 49.00; H, 5.40; B, 2.76; F, 19.38; N, 7.14; O, 8.16; S, 8.17

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: DB04763; DB 04763; DB-04763;

IUPAC/Chemical Name: N/A

InChi Key: CTGXSGQKLGOFLY-UHFFFAOYSA-M

InChi Code: InChI=1S/C16H21N2O2S.BF3.FH/c1-12-10-13(2)18(14(3)11-12)9-8-15-4-6-16(7-5-15)21(17,19)20;2-1(3)4;/h4-7,10-11H,8-9H2,1-3H3,(H2,17,19,20);;1H/q+1;;/p-1

SMILES Code: CC1=[N+](CCC2=CC=C(S(=O)(N)=O)C=C2)C(C)=CC(C)=C1.FB(F)F.[F-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 392.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Smelt CLC, Sanders VR, Newcombe J, Burt RP, Sheppard TD, Topf M, Millar NS. Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor. Neuropharmacology. 2018 Sep 1;139:194-204. doi: 10.1016/j.neuropharm.2018.07.009. Epub 2018 Jul 20. PMID: 30009834; PMCID: PMC6078708.