Oxaflozane hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412583

CAS#: 26629-86-7 (HCl)

Description: Oxaflozane hydrochloride is the salt form of Oxaflozane (free base), a non-tricyclic antidepressant with serotoninergic action. In animals, oxaflozane has anti-cataleptic and anti-aggressive action with weak potentiation of stereotypes provoked by amphetamine. Oxaflozane was developed by Solvay Pharma and marketed in France under tradename Conflictan. The drug was discontinued in 2004.


Chemical Structure

img
Oxaflozane hydrochloride
CAS# 26629-86-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 412583
Name: Oxaflozane hydrochloride
CAS#: 26629-86-7 (HCl)
Chemical Formula: C14H19ClF3NO
Exact Mass:
Molecular Weight: 309.76
Elemental Analysis: C, 54.29; H, 6.18; Cl, 11.44; F, 18.40; N, 4.52; O, 5.17

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 26629-87-8 (free base)   26629-86-7 (HCl)  

Synonym: Oxaflozane hydrochloride; CERM1766; CERM-1766; CERM 1766

IUPAC/Chemical Name: 4-(Isopropyl)-2-(3-(trifluoromethyl)phenyl)morpholine hydrochloride

InChi Key: XYYSVSLSSDHEGA-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H18F3NO.ClH/c1-10(2)18-6-7-19-13(9-18)11-4-3-5-12(8-11)14(15,16)17;/h3-5,8,10,13H,6-7,9H2,1-2H3;1H

SMILES Code: FC(C1=CC(C2CN(C(C)C)CCO2)=CC=C1)(F)F.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 309.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Constantin M, Pognat JF. Comparative study of oxaflozane urinary metabolism in man, the dog and the rat. Identification of the principal metabolites. Arzneimittelforschung. 1979;29(1):109-14. PMID: 582104.

2: Dutertre JP, Barbier P, Suc AL, Jonville AP, Autret E. Oxaflozane overdose in a child. J Toxicol Clin Toxicol. 1992;30(1):123-6. doi: 10.3109/15563659208994452. PMID: 1542141.

3: Hache J, Duchene-Marullaz P, Streichenberger G. Profil pharmacologique d'un nouvel antidépresseur non tricyclique: l'oxaflozane (1.766 Cerm) [Pharmacological profile of a new non tricyclic antidepressant: oxaflozane (1,766 Cerm)]. Therapie. 1974 Jan-Feb;29(1):81-93. French. PMID: 4849381.

4: Rascol A, Maurel H, David J, Layani M. Premiers résultats cliniques d'un nouvel antidépresseur non tricyclique: "loxaflozane" (1766 cerm) [Preliminary clinical results of a new non tricyclic antidepressive drug: oxaflozane]. Therapie. 1974 Jan-Feb;29(1):95-9. French. PMID: 4603757.

5: Cosnier D, Grimal J, Rispat G, Streichenberger G. Propriétés cardiovasculaires de ĺoxaflozane (1,766 CERM) nouvel antiddpresseur non tricyclique [Cardiovascular properties of oxaflozane (1,766 CERM), a new non- tricyclic antidepressive]. Therapie. 1975 Jul-Aug;(4):539-54. French. PMID: 1209529.

6: Denber HC. Trials with drugs outside the United States. Dis Nerv Syst. 1974 Jul;35(7 Pt. 2):8-9. PMID: 17894094.