WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463472
CAS#: 2624131-45-7
Description: PW0787 is an orally bioavailable, brain-penetrant, potent, and selective GPR52 agonist. PW0787 dose-dependently suppresses amphetamine-evoked hyperactivity, suggesting a therapeutic potential for neuropsychiatric diseases.
MedKoo Cat#: 463472
Name: PW0787
CAS#: 2624131-45-7
Chemical Formula: C23H20F4N4O2
Exact Mass: 460.1522
Molecular Weight: 460.4326
Elemental Analysis: C, 60.00; H, 4.38; F, 16.50; N, 12.17; O, 6.95
Synonym: PW0787; PW 0787; PW-0787;
IUPAC/Chemical Name: 1-(6-(3-fluoro-5-(trifluoromethyl)benzyl)pyrimidin-4-yl)-N-(2-hydroxyethyl)indoline-4-carboxamide
InChi Key: OLNVWBLTVAPNME-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H20F4N4O2/c24-16-9-14(8-15(11-16)23(25,26)27)10-17-12-21(30-13-29-17)31-6-4-18-19(2-1-3-20(18)31)22(33)28-5-7-32/h1-3,8-9,11-13,32H,4-7,10H2,(H,28,33)
SMILES Code: O=C(C1=CC=CC2=C1CCN2C3=NC=NC(CC4=CC(C(F)(F)F)=CC(F)=C4)=C3)NCCO
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 460.4326 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
