WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463469

CAS#: unknown

Description: SAJ-310 is a hemoglobin S allosteric modulator. It is a novel potent antisickling agent.

Chemical Structure

CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463469
Name: SAJ-310
CAS#: unknown
Chemical Formula: C14H13NO3
Exact Mass: 243.09
Molecular Weight: 243.262
Elemental Analysis: C, 69.12; H, 5.39; N, 5.76; O, 19.73

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

Synonym: SAJ-310; SAJ310; SAJ 310;

IUPAC/Chemical Name: 5-methoxy-2-(pyridin-2-ylmethoxy)benzaldehyde


InChi Code: InChI=1S/C14H13NO3/c1-17-13-5-6-14(11(8-13)9-16)18-10-12-4-2-3-7-15-12/h2-9H,10H2,1H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 243.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Richter-Addo GB. A structure-guided approach to ameliorate sickle cell disease. Acta Crystallogr D Struct Biol. 2018 Nov 1;74(Pt 11):1039-1040. doi: 10.1107/S2059798318014997. Epub 2018 Oct 30. PMID: 30387762.

2: Deshpande TM, Pagare PP, Ghatge MS, Chen Q, Musayev FN, Venitz J, Zhang Y, Abdulmalik O, Safo MK. Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation. Acta Crystallogr D Struct Biol. 2018 Oct 1;74(Pt 10):956-964. doi: 10.1107/S2059798318009919. Epub 2018 Oct 2. PMID: 30289405; PMCID: PMC6173052.

3: Pagare PP, Ghatge MS, Musayev FN, Deshpande TM, Chen Q, Braxton C, Kim S, Venitz J, Zhang Y, Abdulmalik O, Safo MK. Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease. Bioorg Med Chem. 2018 May 15;26(9):2530-2538. doi: 10.1016/j.bmc.2018.04.015. Epub 2018 Apr 6. PMID: 29655608; PMCID: PMC5935541.