WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463463

CAS#: unknown

Description: ID09 is a Potent Tubulin Polymerization Inhibitor. ID09 showed excellent aqueous solubility and favorable Log P value and displayed noteworthily low nanomolar potency against a variety of tumor cells, including those taxol-resistant ones. ID09 inhibited tubulin polymerization, disrupted cellular microtubule networks by targeting the colchicine site, and promoted HepG2 cell cycle arrest and cell apoptosis. In the HepG2 xenograft mouse model.

Chemical Structure

CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463463
Name: ID09
CAS#: unknown
Chemical Formula: C24H32Cl2N4O3
Exact Mass: 494.1851
Molecular Weight: 495.445
Elemental Analysis: C, 58.18; H, 6.51; Cl, 14.31; N, 11.31; O, 9.69

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ID09; ID 09; ID-09;

IUPAC/Chemical Name: 7-(3-aminopropoxy)-6-ethoxy-N-(3-ethoxyphenyl)-1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amine dihydrochloride


InChi Code: InChI=1S/C24H30N4O3.2ClH/c1-4-29-18-9-6-8-17(14-18)26-24-20-12-16-13-21(30-5-2)22(31-11-7-10-25)15-19(16)23(20)28(3)27-24;;/h6,8-9,13-15H,4-5,7,10-12,25H2,1-3H3,(H,26,27);2*1H


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 495.445 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Cui YJ, Liu C, Ma CC, Ji YT, Yao YL, Tang LQ, Zhang CM, Wu JD, Liu ZP. SAR Investigation and Discovery of Water-Soluble 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazoles as Potent Tubulin Polymerization Inhibitors. J Med Chem. 2020 Nov 17. doi: 10.1021/acs.jmedchem.0c01345. Epub ahead of print. PMID: 33201714.