Pyroxylin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412549

CAS#: 9004-70-0

Description: Pyroxylin is a nitrocellulose solution in ether and alcohol. Collodion has a wide range of uses in industry including applications in the manufacture of photographic film, in fibers, in lacquers, and in engraving and lithography. In medicine it is used as a drug solvent and a wound sealant.


Chemical Structure

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Pyroxylin
CAS# 9004-70-0

Theoretical Analysis

MedKoo Cat#: 412549
Name: Pyroxylin
CAS#: 9004-70-0
Chemical Formula: C18H21N11O38
Exact Mass: 999.0049
Molecular Weight: 999.41
Elemental Analysis: C, 21.63; H, 2.12; N, 15.42; O, 60.83

Price and Availability

Size Price Availability Quantity
100.0mL USD 350.0 2 Weeks
500.0mL USD 550.0 2 Weeks
4.0L USD 1950.0 2 Weeks
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Synonym: Pyroxylin; LR115; LR-115; LR 115

IUPAC/Chemical Name: [(2S,3R,4S,5R,6R)-2-[(2R,3R,4S,5R,6S)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2R,3R,4S,5R,6S)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate

InChi Key: FJWGYAHXMCUOOM-QHOUIDNNSA-N

InChi Code: InChI=1S/C18H21N11O38/c30-19(31)52-1-4-7(58-17-14(65-27(46)47)12(63-25(42)43)9(60-22(36)37)6(56-17)3-54-21(34)35)10(61-23(38)39)13(64-26(44)45)16(55-4)59-8-5(2-53-20(32)33)57-18(67-29(50)51)15(66-28(48)49)11(8)62-24(40)41/h4-18H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11+,12+,13-,14-,15-,16+,17+,18+/m1/s1

SMILES Code: O=[N+]([O-])O[C@@H]1[C@@H](O[N+]([O-])=O)[C@H](O[C@@H]2[C@@H](CO[N+]([O-])=O)O[C@@H](O[C@@H]3[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]3O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]2O[N+]([O-])=O)O[C@H](CO[N+]([O-])=O)[C@H]1O[N+]([O-])=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 999.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kurien BT, Scofield RH. Western blotting. Methods. 2006 Apr;38(4):283-93. doi: 10.1016/j.ymeth.2005.11.007. PMID: 16483794.

2: Lee PY, Osman J, Low TY, Jamal R. Plasma/serum proteomics: depletion strategies for reducing high-abundance proteins for biomarker discovery. Bioanalysis. 2019 Oct;11(19):1799-1812. doi: 10.4155/bio-2019-0145. Epub 2019 Oct 16. PMID: 31617391.

3: Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Nitrocellulose and Collodion as Used in Cosmetics. Int J Toxicol. 2016 Jul;35(1 Suppl):50S-9S. doi: 10.1177/1091581816651607. PMID: 27383197.

4: Greenfield EA. Immunizing Mice and Rats with Nitrocellulose-Bound Antigen. Cold Spring Harb Protoc. 2019 Dec 2;2019(12). doi: 10.1101/pdb.prot100248. PMID: 31792142.

5: Kurien BT, Scofield RH. Isoelectric Focusing on Non-Denaturing Flatbed Gels. Methods Mol Biol. 2019;1855:93-100. doi: 10.1007/978-1-4939-8793-1_9. PMID: 30426410.

6: Kolitz S, Lorsch JR. Protein filter binding. Methods Enzymol. 2014;541:197-205. doi: 10.1016/B978-0-12-420119-4.00016-1. PMID: 24674073.

7: Surendran S, Mathai A, Radhakrishnan VV. Dot-immunobinding assay (Dot-Iba). Methods Mol Biol. 2015;1312:105-8. doi: 10.1007/978-1-4939-2694-7_14. PMID: 26043995.

8: Mazitova NN, Amirov NKh, Berkheeva ZM. Obosnovanie kriticheskogo stazha raboty i kriteriev ranneĭ diagnostiki professional'noĭ i professional'no obuslovlennoĭ patologii u rabotaiushchikh v proizvodstve piroksilinovogo porokha [Bases of critical length of service and criteria of early diagnosis of occupational diseases in workers of pyroxylin powder production]. Med Tr Prom Ekol. 1996;(10):10-5. Russian. PMID: 9064094.

9: Chi J, Gao B, Sun M, Zhang F, Su E, Liu H, Gu Z. Patterned Photonic Nitrocellulose for Pseudopaper ELISA. Anal Chem. 2017 Jul 18;89(14):7727-7733. doi: 10.1021/acs.analchem.7b01732. Epub 2017 Jun 27. PMID: 28622470.

10: Lowe G. Slice blotting. Methods Mol Biol. 2015;1312:87-92. doi: 10.1007/978-1-4939-2694-7_12. PMID: 26043993.

Pyroxylin

100.0mL / USD 350.0