Mafosfamide cyclohexylamine salt

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MedKoo CAT#: 575089

CAS#: 84210-80-0 (CHA salt)

Description: Mafosfamide cyclohexylamine salt is a metabolite of cyclophosphamide.

Chemical Structure

Mafosfamide cyclohexylamine salt
CAS# 84210-80-0 (CHA salt)

Theoretical Analysis

MedKoo Cat#: 575089
Name: Mafosfamide cyclohexylamine salt
CAS#: 84210-80-0 (CHA salt)
Chemical Formula: C15H32Cl2N3O5PS2
Exact Mass: 499.09
Molecular Weight: 500.430
Elemental Analysis: C, 36.00; H, 6.45; Cl, 14.17; N, 8.40; O, 15.99; P, 6.19; S, 12.81

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 88859-04-5 (free acid)   84211-05-2 (sodium)   84210-80-0 (CHA salt)   98845-64-8 (lysine)    

Synonym: Asta Z 7557; ASTA 7557; ASTA7557; ASTA-7557; CCRIS 2542; Mafosfamide cyclohexylamine salt

IUPAC/Chemical Name: cyclohexanamine 2-(((2S,4R)-2-(bis(2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-4-yl)thio)ethane-1-sulfonate


InChi Code: InChI=1S/C9H19Cl2N2O5PS2.C6H13N/c10-2-4-13(5-3-11)19(14)12-9(1-6-18-19)20-7-8-21(15,16)17;7-6-4-2-1-3-5-6/h9H,1-8H2,(H,12,14)(H,15,16,17);6H,1-5,7H2/t9-,19+;/m1./s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 500.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Mazur L, Opydo-Chanek M, Stojak M, Wojcieszek K. Mafosfamide as a new anticancer agent: preclinical investigations and clinical trials. Anticancer Res. 2012 Jul;32(7):2783-9. PMID: 22753738.

2. Jacob E, Scorsone K, Blaney SM, D'Argenio DZ, Berg SL. Synergy of karenitecin and mafosfamide in pediatric leukemia, medulloblastoma, and neuroblastoma cell lines. Pediatr Blood Cancer. 2008 Apr;50(4):757-60. doi: 10.1002/pbc.21330. PMID: 17849472; PMCID: PMC2975705.