WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412453

CAS#: 486-86-2

Description: Caulophylline is an alkaloid from Sophora flavescens with anthelmintic activity.

Chemical Structure

CAS# 486-86-2

Theoretical Analysis

MedKoo Cat#: 412453
Name: Caulophylline
CAS#: 486-86-2
Chemical Formula: C11H14N2O
Exact Mass: 190.1106
Molecular Weight: 190.246
Elemental Analysis: C, 69.45; H, 7.42; N, 14.73; O, 8.41

Price and Availability

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5.0mg USD 333.0 2 Weeks
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Synonym: Caulophylline; BRN-0012448; BRN0012448; BRN 0012448

IUPAC/Chemical Name: (1R)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one


InChi Code: InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1

SMILES Code: O=C1C=CC=C2N1CC3CNC[C@@]2([H])C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 190.246 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Barlow RB, McLeod LJ. Some studies on cytisine and its methylated derivatives. Br J Pharmacol. 1969 Jan;35(1):161-74. doi: 10.1111/j.1476-5381.1969.tb07977.x. PMID: 4387392; PMCID: PMC1703083.

2: Wang XL, Liu BR, Chen CK, Wang JR, Lee SS. Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim. Fitoterapia. 2011 Sep;82(6):793-7. doi: 10.1016/j.fitote.2011.04.010. Epub 2011 May 9. PMID: 21596111.

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5: Wang SC, Chen QH, Wei YY, Li HW, He LC. [Analysis of supercritical fluid extracts of Radix caulophylli with gas chromatography-mass spectrometry]. Yao Xue Xue Bao. 2007 May;42(5):525-8. Chinese. PMID: 17703777.