Catalponol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412437

CAS#: 34168-56-4

Description: Catalponol is a biochemical


Chemical Structure

img
Catalponol
CAS# 34168-56-4

Theoretical Analysis

MedKoo Cat#: 412437
Name: Catalponol
CAS#: 34168-56-4
Chemical Formula: C15H18O2
Exact Mass: 230.1307
Molecular Weight: 230.31
Elemental Analysis: C, 78.23; H, 7.88; O, 13.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Catalponol

IUPAC/Chemical Name: (2R,4S)-4-hydroxy-2-(3-methylbut-2-en-1-yl)-3,4-dihydronaphthalen-1(2H)-one

InChi Key: BTQXIESSQVRLCV-RISCZKNCSA-N

InChi Code: InChI=1S/C15H18O2/c1-10(2)7-8-11-9-14(16)12-5-3-4-6-13(12)15(11)17/h3-7,11,14,16H,8-9H2,1-2H3/t11-,14+/m1/s1

SMILES Code: C/C(C)=C\C[C@@H]1C[C@@H](c2c(C1=O)cccc2)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 230.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Huang HS, Han XH, Hwang BY, Park JI, Yoo SK, Choi HS, Lim SC, Lee MK. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. doi: 10.1080/10286020903193094. PMID: 20183248.

2: Suzuki T, Ismiyarto, Ishizaka Y, Zhou DY, Asano K, Sasai H. One-Pot Catalysis Using a Chiral Iridium Complex/Brønsted Base: Catalytic Asymmetric Synthesis of Catalponol. Org Lett. 2015 Nov 6;17(21):5176-9. doi: 10.1021/acs.orglett.5b02480. Epub 2015 Oct 23. PMID: 26496409.

3: Kil YS, So YK, Choi MJ, Han AR, Jin CH, Seo EK. Cytoprotective dihydronaphthalenones from the wood of Catalpa ovata. Phytochemistry. 2018 Mar;147:14-20. doi: 10.1016/j.phytochem.2017.12.009. Epub 2017 Dec 21. PMID: 29274812.

4: Park BM, Hong SS, Lee C, Lee MS, Kang SJ, Shin YS, Jung JK, Hong JT, Kim Y, Lee MK, Hwang BY. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. doi: 10.1007/s12272-010-0306-2. Epub 2010 Mar 30. PMID: 20361302.

5: Peraza-Sánchez SR, Chávez D, Chai HB, Shin YG, García R, Mejía M, Fairchild CR, Lane KE, Menendez AT, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the roots of Ekmanianthe longiflora. J Nat Prod. 2000 Apr;63(4):492-5. doi: 10.1021/np990528l. PMID: 10785421.

6: Brieskorn CH, Pöhlmann R. Zum Vorkommen eines isomeren Catalponols und von Tectoldimethylather in der Wurzel von Lippia origanoides H.B.K [The occurrence of isomeric catalponol and tectol dimethyl ether in the root of Lippia origanoides H.B.K. (author's transl)]. Arch Pharm (Weinheim). 1976 Oct 10;309(10):829-36. German. doi: 10.1002/ardp.19763091010. PMID: 1008680.

7: McDaniel CA. Major antitermitic components of the heartwood of southern catalpa. J Chem Ecol. 1992 Mar;18(3):359-69. doi: 10.1007/BF00994237. PMID: 24254942.