WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412403
CAS#: 15263-53-3 (free base)
Description: Cartap (free base) is essentially a contact and stomach poison. It is used for the control of chewing and sucking pests and results in insect paralysis.
MedKoo Cat#: 412403
Name: Cartap (free base)
CAS#: 15263-53-3 (free base)
Chemical Formula: C7H15N3O2S2
Exact Mass: 237.0606
Molecular Weight: 237.34
Elemental Analysis: C, 35.43; H, 6.37; N, 17.71; O, 13.48; S, 27.02
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Related CAS #: 15263-52-2 (HCl) 15263-53-3 (free base)
Synonym: Cartap (free base); T1258; T 1258; T-1258
IUPAC/Chemical Name: S,S'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate
InChi Key: IRUJZVNXZWPBMU-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H15N3O2S2/c1-10(2)5(3-13-6(8)11)4-14-7(9)12/h5H,3-4H2,1-2H3,(H2,8,11)(H2,9,12)
SMILES Code: CN(C(CSC(N)=O)CSC(N)=O)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 237.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Wu M, Deng H, Fan Y, Hu Y, Guo Y, Xie L. Rapid Colorimetric Detection of Cartap Residues by AgNP Sensor with Magnetic Molecularly Imprinted Microspheres as Recognition Elements. Molecules. 2018 Jun 14;23(6):1443. doi: 10.3390/molecules23061443. PMID: 29899218; PMCID: PMC6099834.
2: Sharma LP, Kadve MP, Lingaraju MC, Telang AG. Studies on oral subacute toxicity of cartap in male mice. Drug Chem Toxicol. 2019 Jan 7:1-9. doi: 10.1080/01480545.2018.1551900. Epub ahead of print. PMID: 30614290.
3: Kalyaniwala K, Abhilash K, Victor PJ. Cartap Hydrochloride Poisoning. J Assoc Physicians India. 2016 Aug;64(8):91-92. PMID: 27762121.
4: Dai J, Chen H, Gao G, Zhu L, Chai Y, Liu X. Simultaneous determination of cartap and its metabolite in tea using hydrophilic interaction chromatography tandem mass spectrometry and the combination of dispersive solid phase extraction and solid phase extraction. J Chromatogr A. 2019 Aug 30;1600:148-157. doi: 10.1016/j.chroma.2019.04.034. Epub 2019 Apr 13. PMID: 31060785.
5: Emadi M, Maghami P, Khorsandi K, Hosseinzadeh R. Biophysical study on the interaction of cartap hydrochloride and hemoglobin: Heme degradation and functional changes of protein. J Biochem Mol Toxicol. 2019 Jul;33(7):e22325. doi: 10.1002/jbt.22325. Epub 2019 Apr 20. PMID: 31004546.
6: Dong L, Hou C, Fa H, Yang M, Wu H, Zhang L, Huo D. Highly Sensitive Fluorescent Sensor for Cartap Based on Fluorescence Resonance Energy Transfer Between Gold Nanoparticles and Rhodamine B. J Nanosci Nanotechnol. 2018 Apr 1;18(4):2441-2449. doi: 10.1166/jnn.2018.14283. PMID: 29442913.
7: Gupta VK, Siddiqi NJ, Ojha AK, Sharma B. Hepatoprotective effect of Aloe vera against cartap- and malathion-induced toxicity in Wistar rats. J Cell Physiol. 2019 Aug;234(10):18329-18343. doi: 10.1002/jcp.28466. Epub 2019 Mar 19. PMID: 30891764.
8: Liao JW, Kang JJ, Jeng CR, Chang SK, Kuo MJ, Wang SC, Liu MR, Pang VF. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84. doi: 10.1016/j.tox.2005.11.002. Epub 2005 Dec 2. PMID: 16325978.
9: Boorugu HK, Chrispal A. Cartap hydrochloride poisoning: A clinical experience. Indian J Crit Care Med. 2012 Jan;16(1):58-9. doi: 10.4103/0972-5229.94443. PMID: 22557838; PMCID: PMC3338244.
10: Zhou S, Dong Q, Li S, Guo J, Wang X, Zhu G. Developmental toxicity of cartap on zebrafish embryos. Aquat Toxicol. 2009 Dec 13;95(4):339-46. doi: 10.1016/j.aquatox.2009.10.006. Epub 2009 Nov 1. PMID: 19923012.
