WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412386
CAS#: 3463-92-1
Description: Carpaine is an alkaloid originally isolated from Carica papaya that has antiplasmodial and antithrombocytopenic activities. It is active against T. b. rhodesiense, T. cruzi, and P. falciparum. Carpaine (2 mg/kg) inhibits decreases in platelet counts in a rat model of thrombocytopenia induced by busulfan. It decreases systolic, diastolic, and mean arterial blood pressure in anesthetized rats in a dose-dependent manner.
MedKoo Cat#: 412386
Name: Carpaine
CAS#: 3463-92-1
Chemical Formula: C28H50N2O4
Exact Mass: 478.3771
Molecular Weight: 478.72
Elemental Analysis: C, 70.25; H, 10.53; N, 5.85; O, 13.37
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Synonym: Carpaine; EINECS 222-414-2; (+)-Carpaine; (+) Carpaine;
IUPAC/Chemical Name: (1S,11R,13S,14S,24R,26S)-13,26-dimethyl-2,15-dioxa-12,25-diazatricyclo[22.2.2.211,14]triacontane-3,16-dione
InChi Key: AMSCMASJCYVAIF-QCVMBYIASA-N
InChi Code: InChI=1S/C28H50N2O4/c1-21-25-19-17-23(29-21)13-9-5-3-8-12-16-28(32)34-26-20-18-24(30-22(26)2)14-10-6-4-7-11-15-27(31)33-25/h21-26,29-30H,3-20H2,1-2H3/t21-,22-,23+,24+,25-,26-/m0/s1
SMILES Code: C[C@@H]1N[C@@H]2CCCCCCCC(O[C@H]3CC[C@H](N[C@H]3C)CCCCCCCC(O[C@H]1CC2)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 478.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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