WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412383

CAS#: 66203-00-7

Description: Carocainide is an antiarrhythmic drug

Chemical Structure

CAS# 66203-00-7

Theoretical Analysis

MedKoo Cat#: 412383
Name: Carocainide
CAS#: 66203-00-7
Chemical Formula: C18H25N3O5
Exact Mass: 363.1794
Molecular Weight: 363.41
Elemental Analysis: C, 59.49; H, 6.93; N, 11.56; O, 22.01

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Carocainide; BRN5154193; BRN-5154193; BRN 5154193; Carocainidum

IUPAC/Chemical Name: 1-(4,7-Dimethoxy-6-(2-(1-pyrrolidinyl)ethoxy)-5-benzofuranyl)-3-methylurea


InChi Code: InChI=1S/C18H25N3O5/c1-19-18(22)20-13-14(23-2)12-6-10-25-15(12)17(24-3)16(13)26-11-9-21-7-4-5-8-21/h6,10H,4-5,7-9,11H2,1-3H3,(H2,19,20,22)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 363.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Rovei V, Strolin Benedetti M, Daniel C, Moulin A, Donath A. Pharmacokinetics and metabolism of the anti-arrhythmic carocainide in man. Xenobiotica. 1985 Nov;15(11):953-64. doi: 10.3109/00498258509045048. PMID: 4082635.

2: Muramoto J, Hotokebuchi N, Nishi K. Effect of an antiarrhythmic agent, carocainide, on action potentials of ventricular papillary muscle of the guinea- pig heart in vitro. Arch Int Pharmacodyn Ther. 1991 Jul-Aug;312:27-38. PMID: 1772338.

3: Bach P, Steinbeck G. Electrophysiologic and antiarrhythmic effects of carocainide in humans. J Cardiovasc Pharmacol. 1988 Dec;12(6):637-42. doi: 10.1097/00005344-198812000-00003. PMID: 2467080.

4: Zannad F, Aliot E, Baille N, Gilgenkrantz JM. Effets électrophysiologiques du carocaïnide intraveineux [Electrophysiologic effects of intravenous carocainide]. Arch Mal Coeur Vaiss. 1986 Feb;79(2):236-41. French. PMID: 3085623.

5: Huerta F, Pourrias B. Effects of carocainide (770207) on canine cardiac automaticity. Arch Int Pharmacodyn Ther. 1984 Apr;268(2):216-24. PMID: 6732365.

6: Pourrias B, Huerta F, Santamaria R, Tisne Versailles J. Effects of MD770207 (carocainide) on experimental ventricular arrhythmias. Arch Int Pharmacodyn Ther. 1983 May;263(1):85-102. PMID: 6615084.

7: Pourrias B, Santamaria R. Electrophysiological effects of carocainide (770207) on canine ventricular muscle and Purkinje fibers. Arch Int Pharmacodyn Ther. 1983 Sep;265(1):85-95. PMID: 6316863.

8: Huerta F, Santamaria R, Pourrias B. Electrophysiological effects of carocainide (770207) on the dog heart. Arch Int Pharmacodyn Ther. 1984 Feb;267(2):289-98. PMID: 6712362.