WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412353
CAS#: 2622-30-2 (HCl)
Description: Carfenazine, also known as WY-2445, or carphenazine (BAN), also known as carphenazine maleate (USAN) (brand name Proketazine; former developmental code name NSC-71755), is an antipsychotic and tranquilizer of the phenothiazine group that was withdrawn from the market. Carphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
MedKoo Cat#: 412353
Name: Carphenazine HCl
CAS#: 2622-30-2 (HCl)
Chemical Formula: C24H33Cl2N3O2S
Exact Mass:
Molecular Weight: 498.51
Elemental Analysis: C, 57.83; H, 6.67; Cl, 14.22; N, 8.43; O, 6.42; S, 6.43
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Related CAS #: 2622-30-2 (free base) 2975-34-0 (maleate) 2622-30-2 (HCl)
Synonym: NSC-71755; NSC71755; NSC 71755, Carphenazine HCl; Proketazine; Proketazine; Procethazine; carphenazine; NSC 71755; WY2445; WY-2445; WY 2445;
IUPAC/Chemical Name: 1-Propanone, 1-(10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)-, dihydrochloride
InChi Key: XPTAUOGDORJRQP-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H31N3O2S.2ClH/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28;;/h3-4,6-9,18,28H,2,5,10-17H2,1H3;2*1H
SMILES Code: CCC(C(C=C1N2CCCN3CCN(CCO)CC3)=CC=C1SC4=C2C=CC=C4)=O.[H]Cl.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 498.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: MILLER G. EVALUATION OF TWO TRANQUILIZERS: ACETOPHENAZINE MALEATE (TINDAL MALEATE): CARPHENAZINE MALEATE (PROKETAZINE MALEATE). JAMA. 1963 Dec 7;186:943-4. PMID: 14064235.
2: SIMS W. QUALITATIVE AND QUANTITATIVE TESTS FOR CARPHENAZINE MALEATE. J Pharm Sci. 1964 Jan;53:101-3. doi: 10.1002/jps.2600530121. PMID: 14106361.
