WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463307
Description: FAMT is a novel ligand of organic anion transporter OAT1 (SLC22A6), specifically targeting amino acid transporter LAT1 (SLC7A5), exhibiting high renal accumulation.
MedKoo Cat#: 463307
Chemical Formula: C10H12FNO3
Exact Mass: 213.0801
Molecular Weight: 213.2084
Elemental Analysis: C, 56.33; H, 5.67; F, 8.91; N, 6.57; O, 22.51
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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IUPAC/Chemical Name: (S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)-2-methylpropanoic acid
InChi Key: STUMEFJLAPRRME-JTQLQIEISA-N
InChi Code: InChI=1S/C10H12FNO3/c1-10(12,9(14)15)5-6-2-3-8(13)7(11)4-6/h2-4,13H,5,12H2,1H3,(H,14,15)/t10-/m0/s1
SMILES Code: N[C@](CC1=CC=C(O)C(F)=C1)(C)C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 213.2084 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Jin C, Wei L, Ohgaki R, Tominaga H, Xu M, Okuda S, Okanishi H, Kawamoto Y, He X, Nagamori S, Kanai Y. Interaction of halogenated tyrosine/phenylalanine- derivatives with Organic Anion Transporter (OAT) 1 in the renal handling of tumor imaging probes. J Pharmacol Exp Ther. 2020 Sep 27:JPET-AR-2020-000235. doi: 10.1124/jpet.120.000235. Epub ahead of print. PMID: 32981893.