WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412315
CAS#: 944241-52-5
Description: Carbodenafil is a biochemical
MedKoo Cat#: 412315
Name: Carbodenafil
CAS#: 944241-52-5
Chemical Formula: C24H32N6O3
Exact Mass: 452.2536
Molecular Weight: 452.56
Elemental Analysis: C, 63.70; H, 7.13; N, 18.57; O, 10.61
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Synonym: Carbodenafil; Fondenafil; UNII-71OOU63R8M
IUPAC/Chemical Name: 5-(2-ethoxy-5-(4-ethylpiperazine-1-carbonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
InChi Key: BNQTXDVBJLRWNB-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H32N6O3/c1-5-8-18-20-21(28(4)27-18)23(31)26-22(25-20)17-15-16(9-10-19(17)33-7-3)24(32)30-13-11-29(6-2)12-14-30/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,31)
SMILES Code: CCCc1c2c(C(NC(c3c(OCC)ccc(C(N4CCN(CC4)CC)=O)c3)=N2)=O)n(C)n1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 452.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Kee CL, Low MY, Ge X. Isolation and characterization of a novel dithio- carbodenafil analogue from a health supplement. J Pharm Biomed Anal. 2017 Apr 15;137:132-138. doi: 10.1016/j.jpba.2017.01.010. Epub 2017 Jan 16. PMID: 28113089.
2: Bakota EL, Kelly AT, Walterscheid JP, Phatak DR. A Case Report of Fatal Desmethyl Carbodenafil Toxicity. J Anal Toxicol. 2017 Apr 1;41(3):250-255. doi: 10.1093/jat/bkw128. PMID: 27999095.
3: Kee CL, Ge X, Tran CS, Bui QD, Cheah NP, Low MY. Isolation and characterization of N-hydroxyethyl dithio-desethyl carbodenafil from a health supplement. J Pharm Biomed Anal. 2020 Sep 10;189:113431. doi: 10.1016/j.jpba.2020.113431. Epub 2020 Jun 17. PMID: 32599489.
4: Gu Y, Hu Q, Sun J, Yu H, Pan H, Zhao X, Ji S. Isolation and identification of a new sildenafil analogue, hydroxycarbodenafil, found as an adulterant in a health supplement. J Pharm Biomed Anal. 2020 Jun 5;185:113222. doi: 10.1016/j.jpba.2020.113222. Epub 2020 Feb 29. PMID: 32145539.
