WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412287
Description: Captostibone is a biochemical undergoing research against Trypanosoma infections.
MedKoo Cat#: 412287
Chemical Formula: C8H8NaO5SSb
Exact Mass: 359.9028
Molecular Weight: 360.96
Elemental Analysis: C, 26.62; H, 2.23; Na, 6.37; O, 22.16; S, 8.88; Sb, 33.73
This product is not in stock, which may be available by custom synthesis.
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IUPAC/Chemical Name: Acetic acid, ((2-stibonophenyl)thio)-, sodium salt
InChi Key: DXCMIHAZTVCDLW-UHFFFAOYSA-K
InChi Code: InChI=1S/C8H7O2S.Na.2H2O.O.Sb/c9-8(10)6-11-7-4-2-1-3-5-7;;;;;/h1-4H,6H2,(H,9,10);;2*1H2;;/q;+1;;;;+2/p-3
SMILES Code: O=C([O-])CSC1=CC=CC=C1[Sb](O)(O)=O.[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 360.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Gill BS. Treatment of experimental Trypanosoma evansi infection of rodents with captostibone. Trans R Soc Trop Med Hyg. 1971;65(3):347-51. doi: 10.1016/0035-9203(71)90012-5. PMID: 5105319.
2: PACKCHANIAN A. Chemotherapy of African sleeping sickness. III. Chemotherapy of experimental Trypanosoma gambiense and Trypanosoma rhodesiense infections in mice with captostibone. Trans R Soc Trop Med Hyg. 1957 May;51(3):257-64. doi: 10.1016/0035-9203(57)90026-3. PMID: 13443017.