Nitenpyram
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MedKoo CAT#: 412285

CAS#: 150824-47-8

Description: Nitenpyram is a chemical frequently used as an insecticide in agriculture and veterinary medicine. The compound is an insect neurotoxin belonging to the class of neonicotinoids which works by blocking neural signaling of the central nervous system.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 292 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-11-23. Prices are subject to change without notice.

Nitenpyram purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 412285
Name: Nitenpyram
CAS#: 150824-47-8
Chemical Formula: C11H15ClN4O2
Exact Mass: 270.0884
Molecular Weight: 270.78
Elemental Analysis: C, 48.80; H, 5.59; Cl, 13.09; N, 20.70; O, 11.82


Synonym: Nitenpyram; TI304; TI -04; TI 304

IUPAC/Chemical Name: 1,1-Ethenediamine, N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-, (1E)-

InChi Key: CFRPSFYHXJZSBI-DHZHZOJOSA-N

InChi Code: InChI=1S/C11H15ClN4O2/c1-3-15(11(13-2)8-16(17)18)7-9-4-5-10(12)14-6-9/h4-6,8,13H,3,7H2,1-2H3/b11-8+

SMILES Code: O=[N+](/C=C(NC)/N(CC1=CC=C(Cl)N=C1)CC)[O-]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Dai ZL, Yang WL, Fan ZX, Guo L, Liu ZH, Dai YJ. Actinomycetes Rhodococcus ruber CGMCC 17550 degrades neonicotinoid insecticide nitenpyram via a novel hydroxylation pathway and remediates nitenpyram in surface water. Chemosphere. 2020 Oct 17:128670. doi: 10.1016/j.chemosphere.2020.128670. Epub ahead of print. PMID: 33109355.

2: Zhang W, Xia X, Wang J, Zhu L, Wang J, Wang G, Chen Y, Kim YM. Oxidative stress and genotoxicity of nitenpyram to earthworms (Eisenia foetida). Chemosphere. 2020 Oct 4;264(Pt 2):128493. doi: 10.1016/j.chemosphere.2020.128493. Epub ahead of print. PMID: 33039690.

3: Carbonell-Rozas L, Lara FJ, Del Olmo Iruela M, García-Campaña AM. Capillary liquid chromatography as an effective method for the determination of seven neonicotinoid residues in honey samples. J Sep Sci. 2020 Aug 10. doi: 10.1002/jssc.202000611. Epub ahead of print. PMID: 32840966.

4: Mansoor MM, Shad SA. Biochemical mechanism, inheritance and cross-resistance to cyromazine in a non-target Chrysoperla carnea: A potential predator of whiteflies and aphids. Chemosphere. 2020 Dec;260:127620. doi: 10.1016/j.chemosphere.2020.127620. Epub 2020 Jul 16. PMID: 32758770.

5: Paul N, Naik PK, Ribeiro BD, Gooh Pattader PS, Marrucho IM, Banerjee T. Molecular Dynamics Insights and Water Stability of Hydrophobic Deep Eutectic Solvents Aided Extraction of Nitenpyram from an Aqueous Environment. J Phys Chem B. 2020 Aug 27;124(34):7405-7420. doi: 10.1021/acs.jpcb.0c03647. Epub 2020 Aug 17. PMID: 32706582.

6: Wang H, Yang D, Fang H, Han M, Tang C, Wu J, Chen Y, Jiang Q. Predictors, sources, and health risk of exposure to neonicotinoids in Chinese school children: A biomonitoring-based study. Environ Int. 2020 Jul 13;143:105918. doi: 10.1016/j.envint.2020.105918. Epub ahead of print. PMID: 32673906.

7: Yan S, Tian S, Meng Z, Yan J, Jia M, Li R, Zhou Z, Zhu W. Imbalance of gut microbiota and fecal metabolites in offspring female mice induced by nitenpyram exposure during pregnancy. Chemosphere. 2020 Dec;260:127506. doi: 10.1016/j.chemosphere.2020.127506. Epub 2020 Jul 9. PMID: 32673867.

8: Li S, Ren J, Li L, Chen R, Li J, Zhao Y, Chen D, Wu Y. Temporal variation analysis and risk assessment of neonicotinoid residues from tea in China. Environ Pollut. 2020 Nov;266(Pt 2):115119. doi: 10.1016/j.envpol.2020.115119. Epub 2020 Jun 29. PMID: 32623072.

9: Ahmed MAI, Vogel CFA. Toxicological Evaluation of Novel Butenolide Pesticide Flupyradifurone Against Culex quinquefasciatus (Diptera: Culicidae) Mosquitoes. J Med Entomol. 2020 Jun 22:tjaa118. doi: 10.1093/jme/tjaa118. Epub ahead of print. PMID: 32566941.

10: Qayyum MA, Saleem MA, Saeed S, Wakil W, Ishtiaq M, Ashraf W, Ahmed N, Ali M, Ikram RM, Yasin M, Maqsood S, Kiran S, Qaiser MF, Ayaz RA, Nawaz MZ, Abid AD, Khan KA, Alamri SA. Integration of entomopathogenic fungi and eco-friendly insecticides for management of red palm weevil, Rhynchophorus ferrugineus (Olivier). Saudi J Biol Sci. 2020 Jul;27(7):1811-1817. doi: 10.1016/j.sjbs.2019.12.018. Epub 2019 Dec 19. PMID: 32565700; PMCID: PMC7296496.

11: Pang S, Lin Z, Zhang W, Mishra S, Bhatt P, Chen S. Insights Into the Microbial Degradation and Biochemical Mechanisms of Neonicotinoids. Front Microbiol. 2020 May 19;11:868. doi: 10.3389/fmicb.2020.00868. PMID: 32508767; PMCID: PMC7248232.

12: Zhang Y, Zhang Q, Li S, Zhao Y, Chen D, Wu Y. Simultaneous determination of neonicotinoids and fipronils in tea using a modified QuEChERS method and liquid chromatography-high resolution mass spectrometry. Food Chem. 2020 Nov 1;329:127159. doi: 10.1016/j.foodchem.2020.127159. Epub 2020 May 29. PMID: 32497845.

13: Mao K, Ren Z, Li W, Cai T, Qin X, Wan H, Jin BR, He S, Li J. Carboxylesterase genes in nitenpyram-resistant brown planthoppers, Nilaparvata lugens. Insect Sci. 2020 Jun 3. doi: 10.1111/1744-7917.12829. Epub ahead of print. PMID: 32495409.

14: Liu X, Li C, Zhang B, Yuan M, Ma Y, Kong F. A facile strategy for photocatalytic degradation of seven neonicotinoids over sulfur and oxygen co- doped carbon nitride. Chemosphere. 2020 Aug;253:126672. doi: 10.1016/j.chemosphere.2020.126672. Epub 2020 Apr 6. PMID: 32464766.

15: Wang W, Ezell MJ, Lakey PSJ, Aregahegn KZ, Shiraiwa M, Finlayson-Pitts BJ. Unexpected formation of oxygen-free products and nitrous acid from the ozonolysis of the neonicotinoid nitenpyram. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11321-11327. doi: 10.1073/pnas.2002397117. Epub 2020 May 11. PMID: 32393627; PMCID: PMC7260956.

16: Zhang H, Chen A, Shan T, Dong W, Shi X, Gao X. Cross-resistance and Fitness Cost Analysis of Resistance to Thiamethoxam in Melon and Cotton Aphid (Hemiptera: Aphididae). J Econ Entomol. 2020 Aug 13;113(4):1946-1954. doi: 10.1093/jee/toaa090. PMID: 32372079.

17: Li Z, Cai T, Qin Y, Zhang Y, Jin R, Mao K, Liao X, Wan H, Li J. Transcriptional Response of ATP-Binding Cassette (ABC) Transporters to Insecticide in the Brown Planthopper, Nilaparvata lugens (Stål). Insects. 2020 May 2;11(5):280. doi: 10.3390/insects11050280. PMID: 32370222; PMCID: PMC7291042.

18: Liu J, Xiong WH, Ye LY, Zhang WS, Yang H. Developing a Novel Nanoscale Porphyrinic Metal-Organic Framework: A Bifunctional Platform with Sensitive Fluorescent Detection and Elimination of Nitenpyram in Agricultural Environment. J Agric Food Chem. 2020 May 20;68(20):5572-5578. doi: 10.1021/acs.jafc.0c01313. Epub 2020 May 7. PMID: 32348144.

19: Han HS, Yasmin L. Chrysomya bezziana (Diptera: Calliphoridae) infestation in two Malaysian cats treated with oral lotilaner. Vet Dermatol. 2020 Aug;31(4):335-e87. doi: 10.1111/vde.12855. Epub 2020 Apr 22. PMID: 32323413.

20: Tian X, Hong X, Yan S, Li X, Wu H, Lin A, Yang W. Neonicotinoids caused oxidative stress and DNA damage in juvenile Chinese rare minnows (Gobiocypris rarus). Ecotoxicol Environ Saf. 2020 Jul 1;197:110566. doi: 10.1016/j.ecoenv.2020.110566. Epub 2020 Apr 10. PMID: 32283408.