Dansylglycine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 535759

CAS#: 1091-85-6

Description: Dansylglycine is a bioactive chemical.


Chemical Structure

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Dansylglycine
CAS# 1091-85-6

Theoretical Analysis

MedKoo Cat#: 535759
Name: Dansylglycine
CAS#: 1091-85-6
Chemical Formula: C14H16N2O4S
Exact Mass: 308.08
Molecular Weight: 308.352
Elemental Analysis: C, 54.53; H, 5.23; N, 9.09; O, 20.75; S, 10.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Dansylglycine

IUPAC/Chemical Name: N-((5-(Dimethylamino)-1-naphthyl)sulphonyl)glycine

InChi Key: QHFXORCWAQTTGH-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)

SMILES Code: O=C(O)CNS(=O)(C1=C2C=CC=C(N(C)C)C2=CC=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 308.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Bertozo LC, Zeraik ML, Ximenes VF. Dansylglycine, a fluorescent probe for specific determination of halogenating activity of myeloperoxidase and eosinophil peroxidase. Anal Biochem. 2017 Sep 1;532:29-37. doi: 10.1016/j.ab.2017.05.029. Epub 2017 Jun 3. PMID: 28587811.


2: Graciani FS, Ximenes VF. Investigation of human albumin-induced circular dichroism in dansylglycine. PLoS One. 2013 Oct 16;8(10):e76849. doi: 10.1371/journal.pone.0076849. PMID: 24146932; PMCID: PMC3797758.


3: Bramhall J. Use of the fluorescent weak acid dansylglycine to measure transmembrane proton concentration gradients. Biochemistry. 1986 Jul 1;25(13):3958-62. doi: 10.1021/bi00361a033. PMID: 3755615.


4: De Carvalho Bertozo L, Morgon NH, De Souza AR, Ximenes VF. Taurine Bromamine: Reactivity of an Endogenous and Exogenous Anti-Inflammatory and Antimicrobial Amino Acid Derivative. Biomolecules. 2016 Apr 21;6(2):23. doi: 10.3390/biom6020023. PMID: 27110829; PMCID: PMC4919918.


5: Muller N, Lapicque F, Drelon E, Netter P. Binding sites of fluorescent probes on human serum albumin. J Pharm Pharmacol. 1994 Apr;46(4):300-4. doi: 10.1111/j.2042-7158.1994.tb03798.x. PMID: 7519671.


6: Lacaille-Dubois, Franck U, Wagner H. Search for potential angiotensin converting enzyme (ACE)-inhibitors from plants. Phytomedicine. 2001 Jan;8(1):47-52. doi: 10.1078/0944-7113-00003. PMID: 11292239.


7: Robertz GM, Dengler HJ. Endogenous ligand(s) decrease drug--protein binding in uremic sera: a fluorescence probe study. Klin Wochenschr. 1983 Jul 1;61(13):649-53. doi: 10.1007/BF01487581. PMID: 6688447.


8: Marin M, Lhiaubet-Vallet V, Miranda MA. Site-dependent photo-fries rearrangement within serum albumins. J Phys Chem B. 2011 Mar 31;115(12):2910-5. doi: 10.1021/jp2009463. Epub 2011 Mar 8. PMID: 21384817.


9: Dömötör O, Hartinger CG, Bytzek AK, Kiss T, Keppler BK, Enyedy EA. Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. J Biol Inorg Chem. 2013 Jan;18(1):9-17. doi: 10.1007/s00775-012-0944-6. Epub 2012 Oct 18. PMID: 23076343.


10: Ximenes VF, Morgon NH, de Souza AR. Hypobromous acid, a powerful endogenous electrophile: Experimental and theoretical studies. J Inorg Biochem. 2015 May;146:61-8. doi: 10.1016/j.jinorgbio.2015.02.014. Epub 2015 Mar 2. PMID: 25771434.