Canadensolide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412259

CAS#: 20421-31-2

Description: Canadensolide is an antifungal metabolite of Penicillium canadense


Chemical Structure

img
Canadensolide
CAS# 20421-31-2

Theoretical Analysis

MedKoo Cat#: 412259
Name: Canadensolide
CAS#: 20421-31-2
Chemical Formula: C11H14O4
Exact Mass: 210.0892
Molecular Weight: 210.23
Elemental Analysis: C, 62.85; H, 6.71; O, 30.44

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Canadensolide

IUPAC/Chemical Name: Furo(3,4-b)furan-2,4-dione, 6-butyltetrahydro-3-methylene-, (3aS,6R,6aR)-

InChi Key: IYSGHKQBSLXKPO-VGMNWLOBSA-N

InChi Code: InChI=1S/C11H14O4/c1-3-4-5-7-9-8(11(13)14-7)6(2)10(12)15-9/h7-9H,2-5H2,1H3/t7-,8+,9+/m1/s1

SMILES Code: O=C(O[C@]1([H])[C@@]2([H])C(O[C@@H]1CCCC)=O)C2=C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 210.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Li Y, Teng Z, Parkin KL, Wang Q, Zhang Q, Luo W, Ma D, Zhao M. Identification of bioactive metabolites dihydrocanadensolide, Kojic acid, and vanillic acid in soy sauce using GC-MS, NMR spectroscopy, and single-crystal X-ray diffraction. J Agric Food Chem. 2014 Aug 20;62(33):8392-401. doi: 10.1021/jf502159m. Epub 2014 Aug 11. PMID: 25090452.

2: Kelly AR, Kerrigan MH, Walsh PJ. Addition/oxidative rearrangement of 3-furfurals and 3-furyl imines: new approaches to substituted furans and pyrroles. J Am Chem Soc. 2008 Mar 26;130(12):4097-104. doi: 10.1021/ja710988q. Epub 2008 Mar 4. PMID: 18314989.

3: Yu M, Lynch V, Pagenkopf BL. Intramolecular cyclopropanation of glycals: studies toward the synthesis of canadensolide, sporothriolide, and xylobovide. Org Lett. 2001 Aug 9;3(16):2563-6. doi: 10.1021/ol016239h. PMID: 11483061.

4: McCorkindale NJ, Wright JL, Brian PW, Clarke SM, Hutchinson SA. Canadensolide --an antifungal metabolite of Penicillium canadense. Tetrahedron Lett. 1968 Feb;6:727-30. doi: 10.1016/s0040-4039(00)75621-8. PMID: 5640098.