WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412256
Description: Cam 2445 is a nonpeptide, alpha-methyltryptophan derivative; an NK1 neurokinin receptor antagonist that is a potentially useful treatment for arthritis, asthma, migraine, anxiety, psychosis, and emesis.
MedKoo Cat#: 412256
Name: Cam 2445
Chemical Formula: C29H31N3O3
Exact Mass: 469.2365
Molecular Weight: 469.59
Elemental Analysis: C, 74.18; H, 6.65; N, 8.95; O, 10.22
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: Cam 2445; Cam-2445; Cam2445
IUPAC/Chemical Name: 4-methylbenzyl ((R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-1-(((S)-1-phenylethyl)amino)propan-2-yl)carbamate
InChi Key: BQLJONXRHVAQGB-KCWXNJEJSA-N
InChi Code: InChI=1S/C29H31N3O3/c1-20-13-15-22(16-14-20)19-35-28(34)32-29(3,17-24-18-30-26-12-8-7-11-25(24)26)27(33)31-21(2)23-9-5-4-6-10-23/h4-16,18,21,30H,17,19H2,1-3H3,(H,31,33)(H,32,34)/t21-,29+/m0/s1
SMILES Code: C[C@@H](c1ccccc1)NC([C@@](Cc(c[nH]2)c3c2cccc3)(NC(OCc4ccc(C)cc4)=O)C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 469.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Chan OH, Schmid HL, Kuo BS, Wright DS, Howson W, Stewart BH. Absorption of Cam-2445, and NK1 neurokinin receptor antagonist: in vivo, in situ, and in vitro evaluations. J Pharm Sci. 1996 Mar;85(3):253-7. doi: 10.1021/js9503338. PMID: 8699323.