Calphostin C

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MedKoo CAT#: 412247

CAS#: 121263-19-2 (C)

Description: The calphostins are a class of closely related chemical compounds isolated from the fungus Cladosporium cladosporioides. The known calphostins include calphostin A, calphostin B, calphostin C, calphostin D, and calphostin I. The calphostins are inhibitors of protein kinase C (PKC). The most potent member of the series, calphostin C, has found use as a biochemical tool because of this activity.

Chemical Structure

Calphostin C
CAS# 121263-19-2 (C)

Theoretical Analysis

MedKoo Cat#: 412247
Name: Calphostin C
CAS#: 121263-19-2 (C)
Chemical Formula: C44H38O14
Exact Mass: 790.2262
Molecular Weight: 790.77
Elemental Analysis: C, 66.83; H, 4.84; O, 28.32

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1.0mg USD 2330.0 2 Weeks
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Related CAS #: 120461-92-9 (A)   121263-19-2 (C)   124824-06-2 (B)   124857-59-6 (I)   124986-26-1 (D)  

Synonym: Calphostin C; UCN1028C; UCN-1028C; UCN 1028C

IUPAC/Chemical Name: Carbonic acid, 2-(12-(2-(benzoyloxy)propyl)-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl)-1-methylethyl 4-hydroxyphenyl ester


InChi Code: InChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3

SMILES Code: O=C(OC1=CC=C(O)C=C1)OC(C)CC2=C(OC)C(C(C(O)=CC(OC)=C3C4=C(OC)C=C(O)C5=C64)=C3C2=C6C(CC(OC(C7=CC=CC=C7)=O)C)=C(OC)C5=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 790.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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