Calphostin A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412246

CAS#: 120461-92-9 (A)

Description: The calphostins are a class of closely related chemical compounds isolated from the fungus Cladosporium cladosporioides. The known calphostins include calphostin A, calphostin B, calphostin C, calphostin D, and calphostin I. The calphostins are inhibitors of protein kinase C (PKC). The most potent member of the series, calphostin C, has found use as a biochemical tool because of this activity.


Chemical Structure

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Calphostin A
CAS# 120461-92-9 (A)

Theoretical Analysis

MedKoo Cat#: 412246
Name: Calphostin A
CAS#: 120461-92-9 (A)
Chemical Formula: C44H38O12
Exact Mass: 758.2363
Molecular Weight: 758.78
Elemental Analysis: C, 69.65; H, 5.05; O, 25.30

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 120461-92-9 (A)   121263-19-2 (C)   124824-06-2 (B)   124857-59-6 (I)   124986-26-1 (D)  

Synonym: Calphostin A; Ucn1028 A; Ucn-1028 A; Ucn 1028 A

IUPAC/Chemical Name: 3,10-Perylenedione, 1,12-bis(2-(benzoyloxy)propyl)-4,9-dihydroxy-2,6,7,11-tetramethoxy-

InChi Key: DTYXTBFGOFPLIJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C44H38O12/c1-21(55-43(49)23-13-9-7-10-14-23)17-25-31-32-26(18-22(2)56-44(50)24-15-11-8-12-16-24)42(54-6)40(48)34-28(46)20-30(52-4)36(38(32)34)35-29(51-3)19-27(45)33(37(31)35)39(47)41(25)53-5/h7-16,19-22,45-46H,17-18H2,1-6H3

SMILES Code: O=C(C1=C2C(C3=C(OC)C=C(O)C4=C53)=C(OC)C=C1O)C(OC)=C(CC(OC(C6=CC=CC=C6)=O)C)C2=C5C(CC(OC(C7=CC=CC=C7)=O)C)=C(OC)C4=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 758.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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