Caldiamide sodium

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MedKoo CAT#: 412233

CAS#: 122760-91-2 (salt)

Description: Caldiamide sodium is a biochemical

Chemical Structure

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Caldiamide sodium
CAS# 122760-91-2 (salt)
Instruction

Theoretical Analysis

MedKoo Cat#: 412233
Name: Caldiamide sodium
CAS#: 122760-91-2 (salt)
Chemical Formula: C16H28CaN5NaO9
Exact Mass: 497.14
Molecular Weight: 0.000
Elemental Analysis: C, 38.63; H, 5.67; Ca, 8.06; N, 14.08; Na, 4.62; O, 28.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 122760-91-2 (salt)   131410-50-9 (anhydrous)   128326-81-8 (free base)  

Synonym: Caldiamide sodium; UNII1M6415C70M; UNII 1M6415C70M; UNII-1M6415C70M

IUPAC/Chemical Name: calcium sodium 5,8-bis(carboxylatomethyl)-11-(2-(methylamino)-2-oxoethyl)-3-oxo-2,5,8,11-tetraazatridecan-13-oate hydrate

InChi Key: FHOBFNOBIIQSOV-UHFFFAOYSA-K

InChi Code: InChI=1S/C16H29N5O8.Ca.Na.H2O/c1-17-12(22)7-20(10-15(26)27)5-3-19(9-14(24)25)4-6-21(11-16(28)29)8-13(23)18-2;;;/h3-11H2,1-2H3,(H,17,22)(H,18,23)(H,24,25)(H,26,27)(H,28,29);;;1H2/q;+2;+1;/p-3

SMILES Code: CNC(CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(NC)=O)CC([O-])=O)=O.O.[Na+].[Ca+2]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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4: Fretellier N, Idée JM, Guerret S, Hollenbeck C, Hartmann D, González W, Robic C, Port M, Corot C. Clinical, biological, and skin histopathologic effects of ionic macrocyclic and nonionic linear gadolinium chelates in a rat model of nephrogenic systemic fibrosis. Invest Radiol. 2011 Feb;46(2):85-93. doi: 10.1097/RLI.0b013e3181f54044. PMID: 20938344.

5: Grant D, Johnsen H, Juelsrud A, Løvhaug D. Effects of gadolinium contrast agents in naïve and nephrectomized rats: relevance to nephrogenic systemic fibrosis. Acta Radiol. 2009 Mar;50(2):156-69. doi: 10.1080/02841850802637808. PMID: 19160079.

6: Sieber MA, Pietsch H, Walter J, Haider W, Frenzel T, Weinmann HJ. A preclinical study to investigate the development of nephrogenic systemic fibrosis: a possible role for gadolinium-based contrast media. Invest Radiol. 2008 Jan;43(1):65-75. doi: 10.1097/RLI.0b013e31815e6277. PMID: 18097279.

7: Okazaki O, Kurata T, Yoshioka N, Hakusui H. Pharmacokinetics and stability of caldiamide sodium in rats. Arzneimittelforschung. 1996 Jan;46(1):79-83. PMID: 8821523.

8: Lai JJ, Jamieson GC. Determination of dysprosium in monkey serum by inductively-coupled plasma atomic emission spectrometry (ICP-AES) after the administration of Sprodiamide Injection, a new contrast medium for magnetic resonance imaging. J Pharm Biomed Anal. 1993 Nov-Dec;11(11-12):1129-34. doi: 10.1016/0731-7085(93)80093-g. PMID: 8123724.

9: Carvlin MJ, Rajan SS, Rosa L, Muraki AS, Francisco J, Rocklage SM. Efficacy of nonionic low-osmolar gadodiamide injection in animals with intracranial mass lesions. J Magn Reson Imaging. 1992 Jan-Feb;2(1):19-24. doi: 10.1002/jmri.1880020104. PMID: 1623277.