YZ9
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574944

CAS#: 6093-71-6

Description: YZ9 is a potent inhibitor of PFKFB3 (6-phosphfructo-2-kinase/fructose-2,6-bisphosphatase). PFKFB3 is over expressed in many cancers and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YZ9 dose dependently inhibits proliferation of HeLa cells.


Chemical Structure

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YZ9
CAS# 6093-71-6

Theoretical Analysis

MedKoo Cat#: 574944
Name: YZ9
CAS#: 6093-71-6
Chemical Formula: C12H10O5
Exact Mass: 234.0528
Molecular Weight: 234.21
Elemental Analysis: C, 61.54; H, 4.30; O, 34.16

Price and Availability

Size Price Availability Quantity
10.0mg USD 275.0 2 Weeks
50.0mg USD 825.0 2 Weeks
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Synonym: YZ9; YZ 9; YZ-9

IUPAC/Chemical Name: ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate

InChi Key: IETDBZQIWIJQJG-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H10O5/c1-2-16-11(14)9-5-7-3-4-8(13)6-10(7)17-12(9)15/h3-6,13H,2H2,1H3

SMILES Code: O=C1OC2=C(C=CC(O)=C2)C=C1C(OCC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 234.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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YZ9

10.0mg / USD 275.0