9(Z),11(E)-CLA
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463172

CAS#: 756499-04-4

Description: 9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat. It binds to peroxisome proliferator-activated receptor α and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 µM. 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes. Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.

Chemical Structure

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9(Z),11(E)-CLA
CAS# 756499-04-4
Instruction

Theoretical Analysis

MedKoo Cat#: 463172
Name: 9(Z),11(E)-CLA
CAS#: 756499-04-4
Chemical Formula: C18H31NaO2
Exact Mass: 302.22
Molecular Weight: 302.434
Elemental Analysis: C, 71.49; H, 10.33; Na, 7.60; O, 10.58

Price and Availability

Size Price Availability Quantity
10mg USD 350 2 Weeks
25mg USD 950 2 Weeks
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Synonym: 9(Z),11(E)-CLA; 9(Z),11(E) CLA; 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt); cis-9,trans-11-Conjugated Linoleic Acid;

IUPAC/Chemical Name: sodium (9Z,11E)-octadeca-9,11-dienoate

InChi Key: AHGUYUKYUXMSJU-QSZGMOAKSA-M

InChi Code: InChI=1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h7-10H,2-6,11-17H2,1H3,(H,19,20);/q;+1/p-1/b8-7+,10-9-;

SMILES Code: CCCCCC/C=C/C=C\CCCCCCCC([O-])=O.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 302.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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