WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463172
Description: 9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat. It binds to peroxisome proliferator-activated receptor α and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 µM. 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes. Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.
MedKoo Cat#: 463172
Chemical Formula: C18H31NaO2
Exact Mass: 302.2222
Molecular Weight: 302.4338
Elemental Analysis: C, 71.49; H, 10.33; Na, 7.60; O, 10.58
Synonym: 9(Z),11(E)-CLA; 9(Z),11(E) CLA; 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt); cis-9,trans-11-Conjugated Linoleic Acid;
IUPAC/Chemical Name: sodium (9Z,11E)-octadeca-9,11-dienoate
InChi Key: AHGUYUKYUXMSJU-QSZGMOAKSA-M
InChi Code: InChI=1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h7-10H,2-6,11-17H2,1H3,(H,19,20);/q;+1/p-1/b8-7+,10-9-;
SMILES Code: CCCCCC/C=C/C=C\CCCCCCCC([O-])=O.[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 302.4338 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|