3'-O-Methylguanosine
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MedKoo CAT#: 555865

CAS#: 10300-27-3

Description: 3'-O-Methylguanosine, also known as 3-OMG, is a methylated nucleoside analog and a RNA chain terminator. Early virus-​specific RNA synthesis was preferentially inhibited by 3'-​O-​methyl guanosine.


Chemical Structure

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3'-O-Methylguanosine
CAS# 10300-27-3

Theoretical Analysis

MedKoo Cat#: 555865
Name: 3'-O-Methylguanosine
CAS#: 10300-27-3
Chemical Formula: C11H15N5O5
Exact Mass: 297.11
Molecular Weight: 297.271
Elemental Analysis: C, 44.44; H, 5.09; N, 23.56; O, 26.91

Price and Availability

Size Price Availability Quantity
50mg USD 750 2 Weeks
100mg USD 1350 2 Weeks
200mg USD 2250 2 Weeks
500mg USD 3950 2 Weeks
1g USD 6250 2 Weeks
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Synonym: NSC 106541; NSC-106541; NSC106541; 3-OMG; 3'-O-Methylguanosine;

IUPAC/Chemical Name: 2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one

InChi Key: UYARPHAXAJAZLU-KQYNXXCUSA-N

InChi Code: InChI=1S/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

SMILES Code: O=C1N=C(N)NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](OC)[C@H]3O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 297.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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