WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574884

CAS#: 309913-42-6

Description: SX-011 is a p38α inhibitor that also inhibits p38β and JNK-2 but displays no significant activity at p38γ, p38δ, ERK-2 and JNK-1.

Chemical Structure

CAS# 309913-42-6

Theoretical Analysis

MedKoo Cat#: 574884
Name: SX-011
CAS#: 309913-42-6
Chemical Formula: C26H27ClFN3O3
Exact Mass: 483.1725
Molecular Weight: 483.97
Elemental Analysis: C, 64.53; H, 5.62; Cl, 7.32; F, 3.93; N, 8.68; O, 9.92

Price and Availability

Size Price Availability Quantity
10.0mg USD 355.0 2 Weeks
50.0mg USD 1175.0 2 Weeks
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Synonym: SX-011; SX 011; SX011

IUPAC/Chemical Name: 2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide


InChi Code: InChI=1S/C26H27ClFN3O3/c1-29(2)26(34)24(32)21-15-30(3)23-14-22(27)20(13-19(21)23)25(33)31-10-8-17(9-11-31)12-16-4-6-18(28)7-5-16/h4-7,13-15,17H,8-12H2,1-3H3

SMILES Code: O=C(C(N(C)C)=O)C2=CN(C)C1=CC(Cl)=C(C(N3CCC(CC4=CC=C(F)C=C4)CC3)=O)C=C12

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 483.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Lee and Dominguez (2005) MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38α protein. Curr.Med.Chem. 12 2979 PMID: 16378500


10.0mg / USD 355.0