Salbutamol Acetonide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574869

CAS#: 54208-72-9

Description: Salbutamol Acetonide is a Salbutamol derivative. It has higher lipophilicity than Salbutamol which allows an increase of the incorporation efficiency into solid lipid microparticles (SLMs) drug carrier system.

Chemical Structure

Salbutamol Acetonide
CAS# 54208-72-9

Theoretical Analysis

MedKoo Cat#: 574869
Name: Salbutamol Acetonide
CAS#: 54208-72-9
Chemical Formula: C16H25NO3
Exact Mass: 279.1834
Molecular Weight: 279.38
Elemental Analysis: C, 68.79; H, 9.02; N, 5.01; O, 17.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Salbutamol Acetonide

IUPAC/Chemical Name: α-[[(1,1-Dimethylethyl)amino]methyl]-2,2-dimethyl-4H-1,3-benzodioxin-6-methanol


InChi Code: InChI=1S/C16H25NO3/c1-15(2,3)17-9-13(18)11-6-7-14-12(8-11)10-19-16(4,5)20-14/h6-8,13,17-18H,9-10H2,1-5H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 279.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Zhou QT, Qu L, Larson I, Stewart PJ, Morton DA. Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. Int J Pharm. 2010 Jul 15;394(1-2):50-9. doi: 10.1016/j.ijpharm.2010.04.032. Epub 2010 May 7. PMID: 20435112.

2. Stoloff S, Poinsett-Holmes K, Dorinsky PM. Combination therapy with inhaled long-acting beta2-agonists and inhaled corticosteroids: a paradigm shift in asthma management. Pharmacotherapy. 2002 Feb;22(2):212-26. doi: 10.1592/phco. PMID: 11837559.