Gastrofenzin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463049

CAS#: 89845-17-0

Description: Gastrofenzin is an antiulcer drug. It has also been shown to exhibit gonadotropic effects.


Chemical Structure

img
Gastrofenzin
CAS# 89845-17-0

Theoretical Analysis

MedKoo Cat#: 463049
Name: Gastrofenzin
CAS#: 89845-17-0
Chemical Formula: C19H22Cl2N2O2
Exact Mass: 380.11
Molecular Weight: 381.297
Elemental Analysis: C, 59.85; H, 5.82; Cl, 18.59; N, 7.35; O, 8.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Gastrofenzin; Gastrophenzine; Gastrophensin;

IUPAC/Chemical Name: ethyl (4-(4-chlorophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl)carbamate hydrochloride

InChi Key: MYXXVPPYQMJHGO-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H21ClN2O2.ClH/c1-3-24-19(23)21-18-6-4-5-15-16(11-22(2)12-17(15)18)13-7-9-14(20)10-8-13;/h4-10,16H,3,11-12H2,1-2H3,(H,21,23);1H

SMILES Code: CCOC(Nc1c2c(C(c3ccc(Cl)cc3)CN(C2)C)ccc1)=O.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 381.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Antov G, Zaĭkov Kh, Mikhaĭlova A, Khalkova Zh, Popov T, Tasheva M, Mitova S, Dinoeva S, Kapurgov V. Toksikologichna kharakteristika na "Gastrofenzin". III. Khronichna oralna toksichnost [The toxicological characteristics of Gastrofenzin. III. Its chronic oral toxicity]. Probl Khig. 1996;21:96-102. Bulgarian. PMID: 9190605.

2: Mikhaĭlova A, Antov G, Khalkova Zh, Zaĭkov Kh, Tasheva M, Dinoeva S. Toksikologichna kharakteristika na "Gastrofenzin". II. Podostra oralna toksichnost [The toxicological characteristics of Gastrofenzin. II. Its subacute oral toxicity]. Probl Khig. 1996;21:88-96. Bulgarian. PMID: 9190604.

3: Khalkova Zh, Zaĭkov Kh, Antov G, Mikhaĭlova A, Ivanova N. Toksikologichna kharakteristika na "Gastrofenzin". I. Ostra toksichnost (oralna, podkozhna, intravenozna) [The toxicological characteristics of Gastrofenzin. I. Its acute toxicity (oral, subcutaneous and intravenous)]. Probl Khig. 1996;21:81-8. Bulgarian. PMID: 9190603.

4: Ilieva P, Ivanova-Chemishanska L, Antov G. Toksikologichna kharakteristika na "Gastrofenzin". IV. Gonadotropno deĭstvie [The toxicological characteristics of Gastrofenzin. IV. Its gonadotropic action]. Probl Khig. 1996;21:102-6. Bulgarian. PMID: 9190585.

5: Mirkova E. Genotoksichnost i kantserogenen potentsial na gastrofenzin [The genotoxicity and carcinogenic potential of gastrofenzin]. Eksp Med Morfol. 1994;32(3-4):57-68. Bulgarian. PMID: 8857033.

6: Ivanova N, Mondeshka D, Ivanov C, Angelova I, Terziyska S, Paskov V. A new class of antiulcer drugs. I. Antiulcer effect of AN5, a 4-phenyl- tetrahydroisoquinoline derivative, on different experimental models of ulcer in rats. Methods Find Exp Clin Pharmacol. 1990 Jul-Aug;12(6):401-10. PMID: 2087139.