WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574741
CAS#: 1553-60-2
Description: Ibufenac is an analog of the NSAID Ibuprofen that inhibits COX-1 and -2 activity.
MedKoo Cat#: 574741
Name: Ibufenac
CAS#: 1553-60-2
Chemical Formula: C12H16O2
Exact Mass: 192.115
Molecular Weight: 192.26
Elemental Analysis: C, 74.97; H, 8.39; O, 16.64
Synonym: Ibufenac; Dytransin; Ibunac; 4-Isobutylphenylacetic Acid; NSC 99976
IUPAC/Chemical Name: 4-(2-methylpropyl)-benzeneacetic acid
InChi Key: CYWFCPPBTWOZSF-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14)
SMILES Code: CC(C)CC1=CC=C(CC(O)=O)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 192.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Gülcan, H.O., Ünlü, S., Dimoglo, A., et al. Marginally designed new profen analogues have the potential to inhibit cyclooxygenase enzymes. Arch.Pharm.Chem.Life Sci. 348, 55-61 (2015).
