6alpha-Fluorotestosterone

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462858

CAS#: 1597-68-8

Description: 6alpha-Fluorotestosterone is a synthetic nonaromatizable androgen analog of testosterone. It binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone.


Chemical Structure

img
6alpha-Fluorotestosterone
CAS# 1597-68-8

Theoretical Analysis

MedKoo Cat#: 462858
Name: 6alpha-Fluorotestosterone
CAS#: 1597-68-8
Chemical Formula: C19H27FO2
Exact Mass: 306.1995
Molecular Weight: 306.4214
Elemental Analysis: C, 74.48; H, 8.88; F, 6.20; O, 10.44

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Fluorotestosterone; Fluorotestosterone, 6alpha-; U-11207; U 11207; U11207;

IUPAC/Chemical Name: (6S,8R,9S,10R,13S,14S,17S)-6-fluoro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

InChi Key: GGQPTOITOZXLBE-QXROXWLYSA-N

InChi Code: InChI=1S/C19H27FO2/c1-18-7-5-11(21)9-15(18)16(20)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,22H,3-8,10H2,1-2H3/t12-,13-,14-,16-,17-,18+,19-/m0/s1

SMILES Code: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)C[C@@H](C4=CC(CC[C@]34C)=O)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 306.4214 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Kellis JT Jr, Vickery LE. 6 alpha-fluorotestosterone: a nonaromatizable androgen inhibitor of aromatase cytochrome P450. Steroids. 1990 May;55(5):242-6. doi: 10.1016/0039-128x(90)90023-5. PMID: 2360221.

2: Nordeen EJ, Yahr P. Activation and differentiation of sexual behavior and translocation of hypothalamic estrogen receptors in rats by 6 alpha- fluorotestosterone. Horm Behav. 1981 Jun;15(2):123-40. doi: 10.1016/0018-506x(81)90023-4. PMID: 7250906.

3: Choe YS, Katzenellenbogen JA. Synthesis of C-6 fluoroandrogens: evaluation of ligands for tumor receptor imaging. Steroids. 1995 May;60(5):414-22. doi: 10.1016/0039-128x(95)00009-f. PMID: 7570716.

4: Yahr P. Two aromatase inhibitors inhibit the ability of a third to promote mating in male rats. Horm Behav. 2015 Sep;75:41-4. doi: 10.1016/j.yhbeh.2015.07.009. Epub 2015 Jul 29. PMID: 26232614; PMCID: PMC4648640.