WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462858
Description: 6alpha-Fluorotestosterone is a synthetic nonaromatizable androgen analog of testosterone. It binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone.
MedKoo Cat#: 462858
Chemical Formula: C19H27FO2
Exact Mass: 306.1995
Molecular Weight: 306.4214
Elemental Analysis: C, 74.48; H, 8.88; F, 6.20; O, 10.44
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: Fluorotestosterone; Fluorotestosterone, 6alpha-; U-11207; U 11207; U11207;
IUPAC/Chemical Name: (6S,8R,9S,10R,13S,14S,17S)-6-fluoro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChi Key: GGQPTOITOZXLBE-QXROXWLYSA-N
InChi Code: InChI=1S/C19H27FO2/c1-18-7-5-11(21)9-15(18)16(20)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,22H,3-8,10H2,1-2H3/t12-,13-,14-,16-,17-,18+,19-/m0/s1
SMILES Code: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)C[C@@H](C4=CC(CC[C@]34C)=O)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 306.4214 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kellis JT Jr, Vickery LE. 6 alpha-fluorotestosterone: a nonaromatizable androgen inhibitor of aromatase cytochrome P450. Steroids. 1990 May;55(5):242-6. doi: 10.1016/0039-128x(90)90023-5. PMID: 2360221.
2: Nordeen EJ, Yahr P. Activation and differentiation of sexual behavior and translocation of hypothalamic estrogen receptors in rats by 6 alpha- fluorotestosterone. Horm Behav. 1981 Jun;15(2):123-40. doi: 10.1016/0018-506x(81)90023-4. PMID: 7250906.
3: Choe YS, Katzenellenbogen JA. Synthesis of C-6 fluoroandrogens: evaluation of ligands for tumor receptor imaging. Steroids. 1995 May;60(5):414-22. doi: 10.1016/0039-128x(95)00009-f. PMID: 7570716.
4: Yahr P. Two aromatase inhibitors inhibit the ability of a third to promote mating in male rats. Horm Behav. 2015 Sep;75:41-4. doi: 10.1016/j.yhbeh.2015.07.009. Epub 2015 Jul 29. PMID: 26232614; PMCID: PMC4648640.