WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462852
CAS#: unknown
Description: MS4369 is a potent PRMT5 degrader.
MedKoo Cat#: 462852
Name: MS4369
CAS#: unknown
Chemical Formula: C51H76N10O12S
Exact Mass: 1052.5365
Molecular Weight: 1053.287
Elemental Analysis: C, 58.16; H, 7.27; N, 13.30; O, 18.23; S, 3.04
This product is not in stock, which may be available by custom synthesis.
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Synonym: MS4369; MS 4369; MS-4369;
IUPAC/Chemical Name: 6-((1-((S)-19-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amino)-N-((S)-2-hydroxy-3-(piperidin-1-yl)propyl)pyrimidine-4-carboxamide
InChi Key: WIFGJEAVBYEMBK-AXFFDEODSA-N
InChi Code: InChI=1S/C51H76N10O12S/c1-34(36-9-11-37(12-10-36)46-35(2)55-33-74-46)56-49(67)42-23-39(62)29-61(42)50(68)47(51(3,4)5)58-44(64)30-72-21-19-70-17-15-69-16-18-71-20-22-73-31-45(65)60-26-38(27-60)57-43-24-41(53-32-54-43)48(66)52-25-40(63)28-59-13-7-6-8-14-59/h9-12,24,32-34,38-40,42,47,62-63H,6-8,13-23,25-31H2,1-5H3,(H,52,66)(H,56,67)(H,58,64)(H,53,54,57)/t34-,39+,40-,42-,47+/m0/s1
SMILES Code: O=C(C1=NC=NC(NC2CN(C(COCCOCCOCCOCCOCC(N[C@H](C(N3[C@H](C(N[C@H](C4=CC=C(C5=C(C)N=CS5)C=C4)C)=O)C[C@@H](O)C3)=O)C(C)(C)C)=O)=O)C2)=C1)NC[C@H](O)CN6CCCCC6
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 1053.287 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
