U 24067

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462808

CAS#: 1881-07-8

Description: U 24067 is an angiostatic steroid.

Chemical Structure

U 24067
CAS# 1881-07-8

Theoretical Analysis

MedKoo Cat#: 462808
Name: U 24067
CAS#: 1881-07-8
Chemical Formula: C24H31FO5
Exact Mass: 418.22
Molecular Weight: 418.505
Elemental Analysis: C, 68.88; H, 7.47; F, 4.54; O, 19.11

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: EINECS 217-536-8;

IUPAC/Chemical Name: 2-((6S,8S,10R,13S,14S,16R,17R)-6-fluoro-17-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate


InChi Code: InChI=1S/C24H31FO5/c1-13-9-18-16-11-20(25)19-10-15(27)5-7-22(19,3)17(16)6-8-23(18,4)24(13,29)21(28)12-30-14(2)26/h6,10,13,16,18,20,29H,5,7-9,11-12H2,1-4H3/t13-,16-,18+,20+,22-,23+,24+/m1/s1

SMILES Code: C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(CC[C@@]4(C3=CC[C@@]2([C@]1(C(COC(C)=O)=O)O)C)C)=O)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 418.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hori Y, Hu DE, Yasui K, Smither RL, Gresham GA, Fan TP. Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. Br J Pharmacol. 1996 Aug;118(7):1584-91. doi: 10.1111/j.1476-5381.1996.tb15578.x. PMID: 8842418; PMCID: PMC1909851.

2: Pepper MS, Vassalli JD, Wilks JW, Schweigerer L, Orci L, Montesano R. Modulation of bovine microvascular endothelial cell proteolytic properties by inhibitors of angiogenesis. J Cell Biochem. 1994 Aug;55(4):419-34. doi: 10.1002/jcb.240550403. PMID: 7525617.

3: Nguyen M, Shing Y, Folkman J. Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane. Microvasc Res. 1994 Jan;47(1):31-40. doi: 10.1006/mvre.1994.1003. PMID: 7517489.