Galanthamine N-Oxide

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MedKoo CAT#: 574705

CAS#: 134332-50-6

Description: Galanthamine N-Oxide is a metabolite of Galanthamine -- a selective acetylcholinesterase inhibitor.

Chemical Structure

Galanthamine N-Oxide
CAS# 134332-50-6

Theoretical Analysis

MedKoo Cat#: 574705
Name: Galanthamine N-Oxide
CAS#: 134332-50-6
Chemical Formula: C17H21NO4
Exact Mass: 303.1471
Molecular Weight: 303.36
Elemental Analysis: C, 67.31; H, 6.98; N, 4.62; O, 21.10

Price and Availability

Size Price Availability Quantity
2.0mg USD 280.0 2 Weeks
5.0mg USD 425.0 2 Weeks
10.0mg USD 695.0 2 Weeks
25.0mg USD 1205.0 2 Weeks
50.0mg USD 2000.0 2 Weeks
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Synonym: Galanthamine N-Oxide; Nivalin-oxide; Galanthamine 10-Oxide; Galanthamine β-N-oxide

IUPAC/Chemical Name: (4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide


InChi Code: InChI=1S/C17H21NO4/c1-18(20)8-7-17-6-5-12(19)9-14(17)22-16-13(21-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-,18+/m0/s1

SMILES Code: O[C@H]1C=C[C@@]23CC[N@@+](C)([O-])CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 303.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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2: Hsu WY, Lane HY, Lin CH. Medications Used for Cognitive Enhancement in Patients With Schizophrenia, Bipolar Disorder, Alzheimer's Disease, and Parkinson's Disease. Front Psychiatry. 2018 Apr 4;9:91. doi: 10.3389/fpsyt.2018.00091. eCollection 2018. Review. PubMed PMID: 29670547; PubMed Central PMCID: PMC5893641.

3: Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H. Cholinergic medication for antipsychotic-induced tardive dyskinesia. Cochrane Database Syst Rev. 2018 Mar 19;3:CD000207. doi: 10.1002/14651858.CD000207.pub2. Review. PubMed PMID: 29553158.