Febuxostat 67M-1
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574693

CAS#: 887945-96-2

Description: Febuxostat 67M-1 is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation.


Chemical Structure

img
Febuxostat 67M-1
CAS# 887945-96-2

Theoretical Analysis

MedKoo Cat#: 574693
Name: Febuxostat 67M-1
CAS#: 887945-96-2
Chemical Formula: C16H16N2O4S
Exact Mass: 332.08
Molecular Weight: 332.370
Elemental Analysis: C, 57.82; H, 4.85; N, 8.43; O, 19.25; S, 9.65

Price and Availability

Size Price Availability Quantity
5mg USD 225 2 Weeks
10mg USD 380 2 Weeks
25mg USD 665 2 Weeks
50mg USD 1005 2 Weeks
Bulk inquiry

Synonym: Febuxostat 67M-1

IUPAC/Chemical Name: 2-[3-Cyano-4-(3-hydroxy-2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid

InChi Key: FPODSLPQWIIKKI-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H16N2O4S/c1-9(7-19)8-22-13-4-3-11(5-12(13)6-17)15-18-10(2)14(23-15)16(20)21/h3-5,9,19H,7-8H2,1-2H3,(H,20,21)

SMILES Code: O=C(C1=C(C)N=C(C2=CC=C(OCC(C)CO)C(C#N)=C2)S1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 332.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1. Xie H, Wang Z, Deng K, Jiang X, Wang L, Lv G. An HPLC-MS/MS method for simultaneous determination of the active metabolites of febuxostat (67M-1, 67M-2 and 67M-4) in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;970:24-30. doi:10.1016/j.jchromb.2014.08.038

2. Mayer MD, Khosravan R, Vernillet L, Wu JT, Joseph-Ridge N, Mulford DJ. Pharmacokinetics and pharmacodynamics of febuxostat, a new non-purine selective inhibitor of xanthine oxidase in subjects with renal impairment. Am J Ther. 2005;12(1):22-34. doi:10.1097/00045391-200501000-00005