Tyrosine betaine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462785

CAS#: 69168-08-7

Description: Tyrosine betaine is a fungal secondary metabolite from Ephedra roots.

Chemical Structure

Tyrosine betaine
CAS# 69168-08-7

Theoretical Analysis

MedKoo Cat#: 462785
Name: Tyrosine betaine
CAS#: 69168-08-7
Chemical Formula: C12H17NO3
Exact Mass: 223.1208
Molecular Weight: 223.272
Elemental Analysis: C, 64.55; H, 7.67; N, 6.27; O, 21.50

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Maokonine;

IUPAC/Chemical Name: 5-hydroxy-2-(2-(trimethylammonio)ethyl)benzoate


InChi Code: InChI=1S/C12H17NO3/c1-13(2,3)7-6-9-4-5-10(14)8-11(9)12(15)16/h4-5,8H,6-7H2,1-3H3,(H-,14,15,16)

SMILES Code: C[N+](C)(CCc1c(C([O-])=O)cc(O)cc1)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 223.272 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Tamada M, Endo K, Hikino H. Maokonine, hypertensive principle of Ephedra roots. Planta Med. 1978 Nov;34(3):291-3. doi: 10.1055/s-0028-1097453. PMID: 704697.

2: Kawano DF, de Carvalho MR, Machado MFM, Carmona AK, Braga GUL, Carvalho I. Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure. Curr Pharm Des. 2018;24(17):1899-1904. doi: 10.2174/1381612824666180515114236. PMID: 29766796.

3: Carollo CA, Calil AL, Schiave LA, Guaratini T, Roberts DW, Lopes NP, Braga GU. Fungal tyrosine betaine, a novel secondary metabolite from conidia of entomopathogenic Metarhizium spp. fungi. Fungal Biol. 2010 May- Jun;114(5-6):473-80. doi: 10.1016/j.funbio.2010.03.009. Epub 2010 Mar 27. PMID: 20943158.

4: Eggenberger F, Rowell-Rahier M. Physiological sources of variation in chemical defense ofOreina gloriosa (Coleoptera: Chrysomelidae). J Chem Ecol. 1993 Mar;19(3):395-410. doi: 10.1007/BF00994313. PMID: 24248944.