PTN57491
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555830

CAS#: 1355357-49-1

Description: PTN57491 is an key intermediate chemical to synthesize antiviral drugs remdesivir and GS441524. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).


Chemical Structure

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PTN57491
CAS# 1355357-49-1

Theoretical Analysis

MedKoo Cat#: 555830
Name: PTN57491
CAS#: 1355357-49-1
Chemical Formula: C33H31N5O4
Exact Mass: 561.24
Molecular Weight: 561.640
Elemental Analysis: C, 70.57; H, 5.56; N, 12.47; O, 11.39

Price and Availability

Size Price Availability Quantity
100mg USD 950 2 Weeks
200mg USD 1650 2 Weeks
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Synonym: PTN57491; PTN-57491; PTN 57491; GS441524-intermediate; GS 441524-intermediate; GS-441524-intermediate; remdesivir-intermediate; Remdesivir related compound 5;

IUPAC/Chemical Name: (2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carbonitrile

InChi Key: PJXBLWLWNWGFJO-TXLSGFARSA-N

InChi Code: InChI=1S/C33H31N5O4/c34-22-33(29-17-16-27-32(35)36-23-37-38(27)29)31(41-20-26-14-8-3-9-15-26)30(40-19-25-12-6-2-7-13-25)28(42-33)21-39-18-24-10-4-1-5-11-24/h1-17,23,28,30-31H,18-21H2,(H2,35,36,37)/t28-,30-,31-,33+/m1/s1

SMILES Code: N#C[C@@]1(C2=CC=C3C(N)=NC=NN32)O[C@H](COCC4=CC=CC=C4)[C@@H](OCC5=CC=CC=C5)[C@H]1OCC6=CC=CC=C6

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Biological target: To be determined
In vitro activity: To be determined
In vivo activity: To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 561.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: To be determined
In vitro protocol: To be determined
In vivo protocol: To be determined

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