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MedKoo CAT#: 535260


Description: NH-23-C2 is a Novel Caspase 2 inhibitor, selectively blocking caspase-2 activity and caspase-2-mediated MDM-2 cleavage.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-22. Prices are subject to change without notice.

NH-23-C2 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 535260
Name: NH-23-C2
Chemical Formula: C43H51N5O13
Exact Mass: 845.3483
Molecular Weight: 845.903
Elemental Analysis: C, 61.06; H, 6.08; N, 8.28; O, 24.59

Synonym: NH-23-C2

IUPAC/Chemical Name: (5S,8S,11S,14S)-11-((R)-1-(Benzyloxy)ethyl)-5-(carboxymethyl)-1-(2,6-dimethylphenyl)-8-(hydroxymethyl)-14-((S)-indoline-2-carboxamido)-1,4,7,10,13-pentaoxo-2-oxa-6,9,12-triazaoctadecan-18-oic acid


InChi Code: InChI=1S/C43H51N5O13/c1-24-11-9-12-25(2)37(24)43(59)61-23-34(50)31(20-36(53)54)46-41(57)33(21-49)47-42(58)38(26(3)60-22-27-13-5-4-6-14-27)48-39(55)30(17-10-18-35(51)52)45-40(56)32-19-28-15-7-8-16-29(28)44-32/h4-9,11-16,26,30-33,38,44,49H,10,17-23H2,1-3H3,(H,45,56)(H,46,57)(H,47,58)(H,48,55)(H,51,52)(H,53,54)/t26-,30+,31+,32+,33+,38+/m1/s1

SMILES Code: O=C(O)CCC[C@H](NC([C@H]1NC2=C(C=CC=C2)C1)=O)C(N[C@@H]([C@H](OCC3=CC=CC=C3)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(COC(C4=C(C)C=CC=C4C)=O)=O)=O)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: