NEU-4854

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MedKoo CAT#: 535250

CAS#: N/A

Description: NEU-4854 is a novel potent Trypanosoma brucei Inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

NEU-4854 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 535250
Name: NEU-4854
CAS#: N/A
Chemical Formula: C11H11F3N8
Exact Mass: 312.1059
Molecular Weight: 312.2602
Elemental Analysis: C, 42.31; H, 3.55; F, 18.25; N, 35.89


Synonym: NEU-4854; NEU 4854; NEU4854

IUPAC/Chemical Name: N2-(1-Methyl-1H-pyrazol-3-yl)-N6-(2,2,2-trifluoroethyl)-9H-purine-2,6-diamine

InChi Key: NSPKKHFAWIXLDD-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H11F3N8/c1-22-3-2-6(21-22)18-10-19-8(15-4-11(12,13)14)7-9(20-10)17-5-16-7/h2-3,5H,4H2,1H3,(H3,15,16,17,18,19,20,21)

SMILES Code: FC(F)(F)CNC1=C2N=CNC2=NC(NC3=NN(C)C=C3)=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Singh B, Diaz-Gonzalez R, Ceballos-Perez G, Rojas-Barros DI, Gunaganti N, Gillingwater K, Martinez-Martinez MS, Manzano P, Navarro M, Pollastri MP. Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors. J Med Chem. 2020 Aug 13. doi: 10.1021/acs.jmedchem.0c01017. Epub ahead of print. PMID: 32786222.