N-676

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 535241

CAS#: 2275-76-5

Description: N-676 is a bioactive chemical.

Chemical Structure

img
N-676
CAS# 2275-76-5
Instruction

Theoretical Analysis

MedKoo Cat#: 535241
Name: N-676
CAS#: 2275-76-5
Chemical Formula: C23H28ClNO2
Exact Mass: 385.18
Molecular Weight: 385.932
Elemental Analysis: C, 71.58; H, 7.31; Cl, 9.19; N, 3.63; O, 8.29

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: N-676; N 676; N676

IUPAC/Chemical Name: Acetic acid, diphenyl-, 8-ethyl-3alpha-nortropanyl ester, hydrochloride

InChi Key: JHWAYHTWMCXGFC-QYESKELBSA-N

InChi Code: InChI=1S/C23H27NO2.ClH/c1-2-24-19-13-14-20(24)16-21(15-19)26-23(25)22(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-22H,2,13-16H2,1H3;1H/t19-,20+,21+;

SMILES Code: O=C(O[C@@H](C[C@@](CC1)(N2CC)[H])C[C@]12[H])C(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 385.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Weston J, Bromley R, Jackson CF, Adab N, Clayton-Smith J, Greenhalgh J, Hounsome J, McKay AJ, Tudur Smith C, Marson AG. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev. 2016 Nov 7;11(11):CD010224. doi: 10.1002/14651858.CD010224.pub2. PMID: 27819746; PMCID: PMC6465055.


2: DREAMS Trial Collaborators and West Midlands Research Collaborative. Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial). BMJ. 2017 Apr 18;357:j1455. doi: 10.1136/bmj.j1455. PMID: 28420629; PMCID: PMC5482348.


3: Stanton CA, Bansal-Travers M, Johnson AL, Sharma E, Katz L, Ambrose BK, Silveira ML, Day H, Sargent J, Borek N, Compton WM, Johnson SE, Kimmel HL, Kaufman AR, Limpert J, Abrams D, Cummings KM, Goniewicz ML, Tanski S, Travers MJ, Hyland AJ, Pearson JL. Longitudinal e-Cigarette and Cigarette Use Among US Youth in the PATH Study (2013-2015). J Natl Cancer Inst. 2019 Oct 1;111(10):1088-1096. doi: 10.1093/jnci/djz006. PMID: 30689915; PMCID: PMC6792095.


4: Oberbauer AM, Daniels R, Levy K, Famula TR, Mundell P, Kelley R. Maternal omega-3 polyunsaturated fatty acid supplementation on offspring hip joint conformation. PLoS One. 2018 Aug 9;13(8):e0202157. doi: 10.1371/journal.pone.0202157. PMID: 30092106; PMCID: PMC6084972.


5: Asher L, Patel V, De Silva MJ. Community-based psychosocial interventions for people with schizophrenia in low and middle-income countries: systematic review and meta-analysis. BMC Psychiatry. 2017 Oct 30;17(1):355. doi: 10.1186/s12888-017-1516-7. PMID: 29084529; PMCID: PMC5661919.


6: Sebag-Montefiore D, Stephens RJ, Steele R, Monson J, Grieve R, Khanna S, Quirke P, Couture J, de Metz C, Myint AS, Bessell E, Griffiths G, Thompson LC, Parmar M. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet. 2009 Mar 7;373(9666):811-20. doi: 10.1016/S0140-6736(09)60484-0. PMID: 19269519; PMCID: PMC2668947.


7: Ponce OJ, Spencer-Bonilla G, Alvarez-Villalobos N, Serrano V, Singh-Ospina N, Rodriguez-Gutierrez R, Salcido-Montenegro A, Benkhadra R, Prokop LJ, Bhasin S, Brito JP. The efficacy and adverse events of testosterone replacement therapy in hypogonadal men: A systematic review and meta-analysis of randomized, placebo- controlled trials. J Clin Endocrinol Metab. 2018 Mar 17. doi: 10.1210/jc.2018-00404. Epub ahead of print. PMID: 29562341.


8: Assaf-Balut C, Garcia de la Torre N, Durán A, Bordiu E, Del Valle L, Familiar C, Valerio J, Jimenez I, Herraiz MA, Izquierdo N, Runkle I, de Miguel MP, Montañez C, Barabash A, Cuesta M, Rubio MA, Calle-Pascual AL. An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the "Fourth Trimester". J Clin Med. 2019 Sep 19;8(9):1499. doi: 10.3390/jcm8091499. PMID: 31546914; PMCID: PMC6780735.


9: Miyasaki JM, Rheaume C, Gulya L, Ellenstein A, Schwarz HB, Vidic TR, Shanafelt TD, Cascino TL, Keran CM, Busis NA. Qualitative study of burnout, career satisfaction, and well-being among US neurologists in 2016. Neurology. 2017 Oct 17;89(16):1730-1738. doi: 10.1212/WNL.0000000000004526. Epub 2017 Sep 20. PMID: 28931640.


10: Sumarnrote A, Corbel V, Overgaard HJ, Celhay O, Marasri N, Fustec B, Thanispong K, Chareonviriyaphap T. Plasmodium Infections in Anopheles Mosquitoes in Ubon Ratchathani Province, Northeastern Thailand During a Malaria Outbreak. J Am Mosq Control Assoc. 2018 Mar;34(1):11-17. doi: 10.2987/17-6715.1. PMID: 31442122.


11: Paweska JT, Moolla N, Storm N, Msimang V, Conteh O, Weyer J, Vuren PJV. Evaluation of Diagnostic Performance of Three Indirect Enzyme-Linked Immunosorbent Assays for the Detection of IgG Antibodies to Ebola Virus in Human Sera. Viruses. 2019 Jul 24;11(8):678. doi: 10.3390/v11080678. PMID: 31344850; PMCID: PMC6722596.


12: Wang K, Yan H, Xu H, Yang Q, Zhang S, Pan C, Chen H, Zhu H, Liu J, Qu L, Lan X. A novel indel within goat casein alpha S1 gene is significantly associated with litter size. Gene. 2018 Sep 10;671:161-169. doi: 10.1016/j.gene.2018.05.119. Epub 2018 Jun 2. PMID: 29864495.


13: Gamé X, Karsenty G, Ruffion A, Amarenco G, Ballanger P, Chartier-Kastler E, Cosson M, Costa P, Fatton B, Deffieux X, Haab F, Hermieu JF, Le Normand L, Saussine C, Denys P. Hyperactivité vésicale idiopathique et BOTOX(®): revue de la littérature [Idiopathic overactive bladder and BOTOX(®): Literature review]. Prog Urol. 2015 Jun;25(8):461-73. French. doi: 10.1016/j.purol.2015.01.006. Epub 2015 Feb 3. PMID: 25662706.


14: Müller AM, Langwieser N, Bradaric C, Haller B, Fusaro M, Ott I, von Beckerath N, Kastrati A, Laugwitz KL, Ibrahim T. Endovascular Treatment for Steno-Occlusive Iliac Artery Disease: Safety and Long-Term Outcome. Angiology. 2018 Apr;69(4):308-315. doi: 10.1177/0003319717720052. Epub 2017 Jul 27. PMID: 28747061.


15: Rodu B, Plurphanswat N. Quit Methods Used by American Smokers, 2013-2014. Int J Environ Res Public Health. 2017 Nov 17;14(11):1403. doi: 10.3390/ijerph14111403. PMID: 29149048; PMCID: PMC5708042.


16: Henning O, Nakken KO, Lossius MI. People with epilepsy and their relatives want more information about risks of injuries and premature death. Epilepsy Behav. 2018 May;82:6-10. doi: 10.1016/j.yebeh.2018.02.023. Epub 2018 Mar 23. PMID: 29574300.


17: Sharma R, Costa Santos L, da Silva RA, Gonçalves CV, de Melo Calado S, Santos DP, de Andrade de Melo JP, de Cássia Pontello Rampazzo R, Requião L, Krieger MA, Barral-Netto M, de Oliveira CI. Surveillance of donated blood during the 2016 arbovirus outbreak in Brazil. J Med Virol. 2018 Aug;90(8):1406-1410. doi: 10.1002/jmv.25193. Epub 2018 Apr 26. PMID: 29667206.


18: Kaltenbach B, Brandenbusch V, Möbus V, Mall G, Falk S, van den Bergh M, Chevalier F, Müller-Schimpfle M. A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies. Eur J Radiol. 2017 Jan;86:221-226. doi: 10.1016/j.ejrad.2016.11.022. Epub 2016 Nov 23. PMID: 28027751.


19: Omar A, Macke C, Winkelmann M, Beckmann E, Mommsen P, Schröter C, Krettek C, Zeckey C. Limited influence of blunt aortic injuries on the outcome of polytraumatized patients: a matched pair analysis. Arch Orthop Trauma Surg. 2018 Feb;138(2):211-218. doi: 10.1007/s00402-017-2842-4. Epub 2017 Nov 15. PMID: 29143168.


20: Huf SW, Volpp KG, Asch DA, Bair E, Venkataramani A. Association of Medicaid Healthy Behavior Incentive Programs With Smoking Cessation, Weight Loss, and Annual Preventive Health Visits. JAMA Netw Open. 2018 Dec 7;1(8):e186185. doi: 10.1001/jamanetworkopen.2018.6185. PMID: 30646327; PMCID: PMC6324555.