WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462561

CAS#: 1801873-49-3

Description: OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction, while OICR-0547 is an inactive control compound that no longer binds to WDR5.

Chemical Structure

CAS# 1801873-49-3

Theoretical Analysis

MedKoo Cat#: 462561
Name: OICR-0547
CAS#: 1801873-49-3
Chemical Formula: C28H29F3N4O4
Exact Mass: 542.2141
Molecular Weight: 542.5592
Elemental Analysis: C, 61.99; H, 5.39; F, 10.50; N, 10.33; O, 11.80

Price and Availability

Size Price Availability Quantity
5.0mg USD 310.0 2 Weeks
10.0mg USD 520.0 2 Weeks
25.0mg USD 900.0 2 Weeks
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Synonym: OICR-0547; OICR 0547; OICR0547

IUPAC/Chemical Name: N-(4-morpholino-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide


InChi Code: InChI=1S/C28H29F3N4O4/c29-28(30,31)23-16-26(36)32-17-22(23)27(37)33-24-15-21(4-5-25(24)35-8-12-39-13-9-35)20-3-1-2-19(14-20)18-34-6-10-38-11-7-34/h1-5,14-17H,6-13,18H2,(H,32,36)(H,33,37)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 542.5592 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Grebien F, Vedadi M, Getlik M, et al. Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia [published correction appears in Nat Chem Biol. 2015 Oct;11(10):815]. Nat Chem Biol. 2015;11(8):571-578. doi:10.1038/nchembio.1859