NVP-BSK805 dihydrochloride

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MedKoo CAT#: 462550

CAS#: 1942919-79-0

Description: NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 350 2 Weeks
10mg USD 540 2 Weeks
10mg USD 1170 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-28. Prices are subject to change without notice.

NVP-BSK805 dihydrochloride is in stock.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 462550
Name: NVP-BSK805 dihydrochloride
CAS#: 1942919-79-0
Chemical Formula: C27H30Cl2F2N6O
Exact Mass: 562.1826
Molecular Weight: 563.4748
Elemental Analysis: C, 57.55; H, 5.37; Cl, 12.58; F, 6.74; N, 14.91; O, 2.84

Synonym: NVP-BSK805 dihydrochloride; NVP BSK805 dihydrochloride; NVPBSK805 dihydrochloride

IUPAC/Chemical Name: 4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine dihydrochloride


InChi Code: InChI=1S/C27H28F2N6O.2ClH/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20;;/h1-3,12-16,20,30H,4-11,17H2;2*1H


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Baffert F, Régnier CH, De Pover A, et al. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. Mol Cancer Ther. 2010;9(7):1945-1955. doi:10.1158/1535-7163.MCT-10-0053

2: Cheon JH, Kim KS, Yadav DK, Kim M, Kim HS, Yoon S. The JAK2 inhibitors CEP-33779 and NVP-BSK805 have high P-gp inhibitory activity and sensitize drug-resistant cancer cells to vincristine. Biochem Biophys Res Commun. 2017;490(4):1176-1182. doi:10.1016/j.bbrc.2017.06.178